Pueraria lobata

Pueraria lobata

(Ben Jing)

[synonyms] gange (Yan's Xiao'er Fang), gange (Diannan materia medica), fenge (caombianfang), gemaru (Luchuan materia medica), geyugen (Shandong traditional Chinese Medicine), Huangge (Sichuan Traditional Chinese medicine records), getiaogan (Shaanxi traditional Chinese medicine records).

[source] it is the tuberous root of Pueraria lobata.

[plant morphology] Ge (the book of songs), also known as Jiqi (the book of songs), daocao (Shuowen), Luhuo, Huangjin (bielu), huanggeteng (Tianbao materia medica), yebiange.

Perennial liana, 10 meters long, covered with yellowish brown coarse hairs. The root is thick. The leaves are alternate, with long petioles, 3 compound leaves, the petioles of apical leaflets are longer, the leaves are rhomboid round, sometimes with 3 wavy lobes, 8-19 cm long and 6.5-18 cm wide, the apex is acute, the base is round, both sides are covered with white pubescence, and the lower part is dense; the lateral leaflets are smaller, elliptic or rhomboid elliptic, sometimes with 2-3 wavy lobes. Raceme axillary, pedicel densely covered with yellow white tomentose; flowers dense; bracts narrowly linear, caducous, bracteoles linear lanceolate; butterfly flowers blue purple or purple, 15-19 cm long; calyx 5-toothed, calyx teeth lanceolate; flag petal suborbicular or ovoid, apex concave, base with two short ears, wing petal narrowly elliptic, shorter than flag petal, usually only one base has ears, keel petal The ovary is linear and the style is curved. Pods linear, flat, 6-9 cm long, 7-10 mm wide, densely covered with yellowish brown long bristles. Seeds oval and flat, reddish brown, glossy. The flowering period is from April to August. The fruit period is from August to October.

It grows in the grass on the hillside or on the roadside or in the shady and wet places. It is distributed in Liaoning, Hebei, Henan, Shandong, Anhui, Jiangsu, Zhejiang, Fujian, Taiwan, Guangdong, Guangxi, Jiangxi, Hunan, Hubei, Sichuan, Guizhou, Yunnan, Shanxi, Shaanxi, Gansu, etc.

The vine (Pueraria lobata), leaf (Pueraria lobata), flower (Pueraria lobata) and seed (Pueraria lobata) of this plant are also used for medicine. Please refer to the special section for details.

[collection] collect in spring and autumn, wash, remove skin, slice, sun dry or dry. After slicing, they were soaked in brine, alum water or rice washing water, then smoked with sulfur yellow and dried in the sun.

[medicinal materials] the dried root tubers are long cylindrical in shape. Most of the medicinal materials are cut lengthwise or obliquely into plate-shaped thick slices with different lengths, about 20 cm in length, 5-10 cm in diameter and 0.7-1.3 cm in thickness. White or light brown, the surface sometimes visible residual brown skin, rough section, strong fiber. It is hard and heavy, rich in powder, and contains a lot of fibers. The concentric ring layer formed by fibers can be seen in the cross section, and the longitudinal section shows the alternation of fiber and powder, forming longitudinal lines. Odorless and sweet. It is better to have large, solid, white color, enough powder and less fiber; it is better to have loose, yellow color, no powder and more fiber.

It is mainly produced in Henan, Hunan, Zhejiang and Sichuan.

In addition to the above authentic products, there are also edible roots of Pueraria lobata, Pueraria omeiensis, Pueraria lobata, Pueraria lobata, etc., which are also used as Pueraria lobata in a few areas.

[chemical constituents] puerarin, puerarin xyloside, daidzein, daidzein glycoside, β - sitosterol and arachidonic acid are the isoflavones in Pueraria lobata. It also contains a large amount of starch (19-20% in fresh Pueraria lobata).

The dry root of Caulis Puerariae contains 37% starch.

The root of Pueraria lobata contains 15-20% starch.

Puerarin, daidzein, daidzein glycosides, β - sitosterol, 4 ′, 6 ″ - diacetyl puerarin and stigmasterol were isolated from the roots of Indian plants of the same genus.

[pharmacological action] 1. Effects on circulatory system

Flavonoids from Pueraria lobata can increase blood flow of brain and coronary artery. After injecting puerarin into internal carotid artery of anesthetized dogs, the cerebral blood flow increased and the vascular resistance decreased correspondingly, and the effect lasted for 2-20 minutes. If injected intravenously, the cerebral blood flow increased slightly, and the effect of epinephrine and norepinephrine on the contraction of cerebral vessels could not be relieved, but it could improve the cerebral circulation in patients with high blood pressure arteriosclerosis, and its effect was mild. Puerarin flavone and puerarin alcohol extract were injected into the coronary artery and vein of dogs, which could increase the coronary blood flow and reduce the vascular resistance. Intraperitoneal and subcutaneous injection of Pueraria wine extract and intraperitoneal injection of Pueraria Decoction and the crystals from Pueraria have protective effects on cardiac ischemic response induced by pituitrin. Oral administration of Pueraria decoction has no obvious antihypertensive effect on hypertensive dogs. Pueraria (made in Japan) decoction is reported to have two components: exciting and inhibiting heart.

② Antispasmodic effect

Both Chinese Pueraria (varieties not indicated) and Japanese Pueraria contain Tiandou flavone, which has papaverine like antispasmodic effect on isolated intestine of mice and guinea pigs. However, the antispasmodic effect of Chinese Pueraria is stronger than that of Japanese Pueraria, which may be related to its large content and more flavones. This antispasmodic component has the effect of antihistamine and acetylcholine; other isoflavones isolated from Japanese Pueraria are derived However, there was no obvious acetylcholine expansion effect of the compound. The muscarinic effect of mtf-101 from Pueraria lobata was also observed.

③ Hypoglycemic effect

After oral administration of Pueraria lobata Decoction to rabbits, the blood glucose increased in the first 2 hours, then decreased, and decreased the lowest in the third and fourth hours. It not only had no antagonistic effect on adrenaline induced hyperglycemia in rabbits, but increased it, but promoted the blood glucose to return to normal early. The water extract of Pueraria lobata can also make the blood glucose of rabbits rise at the beginning and then decrease, and it has more significant effect on the blood glucose of osmium starved rabbits, but the ether extract has no obvious effect on the glucose metabolism.

④ Antipyretic and estrogen like effects

Pueraria extract from Japan has obvious antipyretic effect on rabbits with artificial fever, lasting for 4-5 hours. Pueraria lobata can increase the weight of uterus in immature mice and has estrogen like effect. Daidzein is the effective component of this action.

[processing] Radix Puerariae: remove impurities, wash, soak in water, remove, moisten, slice and dry in time. Simmer Radix Puerariae: first sprinkle a small amount of bran into the hot pot, wait for the smoke, pour the Puerariae slices into it, cover the remaining bran on it, simmer until the bran on the lower layer is burnt yellow. Then turn the puerariae and bran continuously with a shovel until the Puerariae slices are dark yellow. Take them out, screen the bran and cool them thoroughly. (100 Jin per Pueraria, 25 Jin per bran)

"The essence of pinhui": "kudzu root, scrape off skin or mash juice. "

[flavor] Gan Xin, Ping.

① Ben Jing: "it tastes sweet and flat. "

② Bielu: "non toxic. Rooting juice, cold. "

③ "Gangmu": "Gan Xin, Ping, non-toxic. "

[channel tropism] entering spleen and stomach channels.

① Zhang Yuanyuan: "it's popular in zuyangmingjing. "

② New edition of materia medica: "into the stomach, and into the lung. "

③ "Seeking truth from Materia Medica" says: "entering the stomach, entering the spleen at the same time. "

④ "Yao Yao Fen Ji": it goes into the stomach and bladder meridian, and also into the spleen meridian. "

[function indications] it can promote Yang and relieve muscle, relieve rash and diarrhea, remove trouble and stop temperature. For typhoid fever, warm heat, headache, fever, thirst, diarrhea, dysentery, rash, hypertension, angina, deafness.

① Ben Jing: "it is mainly used to quench thirst, body heat, vomiting, arthralgia, Yin Qi and detoxification. "

② Bielu: "treating typhoid, apoplexy, headache, resolving muscle, publishing, sweating, and opening the mind.". It can cure golden sores, relieve pain, and relieve hypochondriac pain. "Rooting juice can cure thirst, typhoid and heat. "

③ "Ben Cao Jing Ji Zhu": "Sha Ye Ge, Ba Dou, Bai Yao Du. "

④ Tao Hongjing: "if you are alive, you can drink juice to relieve febrile diseases. Radix puerariae is a kind of scurf, which can cure golden sores and cut off blood, as well as malaria and sores. "

⑤ According to the theory of medicinal properties, "it can cure heaven, promote qi, emesis, appetizer and food, and relieve alcohol and poison, and stop thirst. Boil the crumb to cure the golden sores, cure the disease and relieve the fever. "

⑥ "Tang materia medica:" at the end of taking it, the master is a dog, and drink its juice well. "

⑦ Materia medica notes: "the living have broken blood, mixed sores, abortion, detoxification of alcohol, red body heat, yellow wine, red and astringent urine. "

⑧ Rihuazi materia medica: "it can cure chest diaphragmatic heat, upset and sultry, stop bleeding and dysentery, dredge small intestine, expel pus and blood, and apply snake and insect. "

⑨ "Kaibao Materia Medica": "children with hot ruffian, drink it with pueraria root. "

⑩ "Qi Yuan of medicine": "in addition to spleen and stomach deficiency heat and thirst. "

(11) Zhang Yuanyuan: "it is difficult to spread the exterior evil, and it is difficult to spread the children's sore rash. "

(12) the compendium of Medical Sciences: "dispersing stagnant fire. "

[usage and dosage] oral administration: decoct soup, 1.5 ~ 3 yuan; or mash juice. External use: tamping.

[taboo] Zhang Yuanyuan: "don't take too much for fear of damaging stomach qi. "

② Ben Cao Zheng: "it is cool in nature and easy to move and vomit. It should be used with caution for those with cold stomach. "

③ "From the new materia medica:" in summer, excessive sweating is especially taboo. "

[prescription selection] ① for the treatment of Dayang disease, the neck is stronger than the back, and there is no sweating wind: four taels of kudzu, three taels of Mahuang, two taels of Guizhi, three taels of ginger, two taels of licorice, two taels of Paeonia and twelve jujubes. First, boil Mahuang and kudzu in a bucket of water, reduce two liters, remove the white foam, take all kinds of medicine, boil three liters, remove the dregs, take one liter warm, and take it slightly like sweat. (Gegen Decoction in Treatise on Febrile Diseases)

② In the treatment of Taiyang disease and Guizhi syndrome, the treatment is counter to the treatment, and the benefit is more than enough. The pulse is promoted (the surface is not solved), and the sweat is caused by panting: Radix Puerariae half Jin, Radix Glycyrrhizae two Liang (fried), Radix Scutellariae three Liang, Rhizoma Coptidis three Liang. For the first four flavors, take eight liters of water. First boil the pueraria, reduce two liters, take all the herbs, boil two liters, remove the dross, and then take it at different temperatures. (Gegen Huangqin Huanglian Decoction in Treatise on Febrile Diseases)

③ Treatment of typhoid fever, wind heat, headache, limb pain, rash has not occurred: Cimicifuga, dried Pueraria (file), peony, licorice (file, fried) each equal. The same as the coarse powder, each serving four money, water one and a half, fried to one, the amount and size

Chinese PinYin : Ge Gen