Closed at night

Closed at night

(classified herbal medicine)

[synonyms] grab, Mazhu (Erya), clover (Diannan materia medica), fengcao (questioning materia medica), junchuanzi (classified herbal medicine), yejicao, baimazhui, zhaogongbian, yebihancao, tiexianbacao (domestic herbage plant), shedaotui, shetui Cao (Guizhou folk medicine Collection), qianliguang, huweiyi, bantianlei, huhuzui, locust Chuang, closed door Grass, dark grass (Fujian folk herbal medicine), Herba Leonuri, Rhizoma tieverbenae (Jiangxi folk herbal medicine), antipyretic grass, small species yeguancao, snake shelling, yizhijian, yijixiang (Guizhou folk medicine), huliuchuan, qianliji (Minnan folk herbal medicine), snake flaking skin (Sichuan Traditional Chinese medicine records), fengjiaowei, huashicao (Hunan medicine records), baimencao, guangmenzhu, Yehe Grass (Mindong materia medica), clover grass, iron broom, Yinyang grass, xiaoyemishaichai, daliwang (Jiangxi folk herbal prescription), menmenmencao, horsetail grass, yeguan grass (Zhejian folk herbal medicine), huoyucao, shiqingpeng (Shanghai Chinese herbal medicine), Feiyi (Fujian Chinese herbal medicine), chuanyuchuan, chuanyucao (Yunnan Chinese herbal medicine), huangshiteng (Kunming Chinese herbal medicine) In the Ming Dynasty, traditional Chinese herbal medicine was commonly used.

[source] the whole grass or the whole grass with roots of legumes.

[plant morphology] leaf cutting iron broom, also known as Lespedeza sericea and Lespedeza microphylla.

Small erect shrub, up to 1 m high. Branches slender, thinly puberulent. 3 compound leaves alternate, dense, petiole very short, less than 2 mm long; leaflets very small, linear cuneate, 4-10 mm long, apex obtuse or truncate, with small sharp, tapering below the middle, usually nearly bald above, covered with gray hairs below. Flowers 1-4 in leaf axils, with very short petiole; bracteoles ovate; calyx 3-4 mm long, 5-lobed, lobes linear conic, pilose; corolla butterfly shaped, yellow white, with purple spots, in the lower bouquet, often without petals; petal elliptic, clawed, keel not very curved; stamen 10, 2-body; pistil 1, ovary superior, style curved, stigma small, terminal. Pods small, sessile, ca. 3 mm long, thinly silky. The flowering period is from June to September. The fruiting period is October.

Born on hillside, wasteland or roadside. Distributed in Northeast, Shandong, Jiangsu, Zhejiang, Jiangxi, Hubei, Hunan, Sichuan, Yunnan, Fujian, Guangdong, Guangxi, Guizhou and other places.

[collection] harvested from September to October, fresh or dried.

[chemical constituents] it contains pinritol, flavonoids, phenolic compounds, tannins and β - sitosterol.

(1) antitussive effect

The mice were given oral decoctions and 0.5 grams of ctningol, 707 mg, or 5, or 607, mainly phenolic compounds, with a small amount of flavonoids and acidic substances, and 10 mg, which had significant antitussive effects (ammonia spray). The intensity of action was about the same as that of codeine 2 mg per rat. However, the method of inducing cough by electric stimulation of the superior laryngeal nerve in anesthetized cats can not prove that kenitol and "707" have antitussive effect, because their antitussive effect does not directly affect the central nervous system. Oral administration of β - sitosterol 500 mg / kg in mice has significant antitussive effect.

② Expectorant effect

There was no obvious expectorant effect when mice were orally administered with 75 mg of "707" or "607" (phenol red method), but it had certain expectorant or expectorant effect in clinical application.

③ Antiasthmatic effect

Intraperitoneal injection of "707" 100~200 mg / kg in guinea pigs had obvious antiasthmatic effect (histamine spray method). The effect of cineol 200 mg / kg was not obvious. The results of isolated guinea pig trachea test showed that "707" had an antihistamine effect and an obvious aminophylline like relaxing effect on tracheal smooth muscle, but the action time was slower and longer than that of aminophylline.

④ Effect on uterus

The ethanol extract of root has selective excitatory effect on the uterus of pregnant animals and the uterus sensitized by diethylstilbestrol, but has no obvious effect on the uterus of non pregnant animals.

⑤ Antibacterial action

In vitro test showed that the whole herb decoction had antibacterial effect on Staphylococcus aureus, Diplococcus pneumoniae, Streptococcus A and Catacoccus at the concentration of 6.25-25%. The content of "707" was more than 5 mg / ml, it had inhibitory effect on Staphylococcus albicans, and more than 10 mg / ml had inhibitory effect on Streptococcus a. The results showed that kenitol and "607" had no inhibitory effect on the above bacteria.

Bitter, pungent and cool.

① "Diannan Materia Medica": "the nature is slightly warm, the taste is pungent and slightly bitter. "

② Fujian folk herbal medicine: "bitter and pungent, slightly cold. "

③ Sichuan Traditional Chinese medicine annals: "it is warm in nature, light in taste and non-toxic. "

④ Common folk herbs in Kunming: "pungent, slightly bitter, flat. "

[Guijing] Mindong materia medica: "entering lung, liver and kidney. "

Functions and indications: tonifying liver and kidney, benefiting lung and Yin, dispersing blood stasis and detumescence. It is used to treat spermatorrhea, enuresis, leucorrhea, asthma, stomachache, fatigue, infantile malnutrition, diarrhea, traumatic injury, vision loss, red eyes and mastitis.

① "Diannan Materia Medica": "treating sore, swelling and toxin, dispersing sore and carbuncle. "

② Questioning materia medica: "for the treatment of traumatic injuries, it can be fried and steamed to disperse blood stasis. "

③ Classification of herbal medicine: "treatment of red collapse, leucorrhea, dysentery."..

④ Fujian folk herbal medicine: "Yigan, Mingmu, diuretic, antipyretic. "

⑤ "Guizhou folk medicine": "treat knife wounds, close the anus, treat jaundice, Shujin Huoxue. "

⑥ Sichuan Traditional Chinese medicine annals: "it can cure weak enuresis, male leucorrhea, female leucorrhea, yin deficiency and Qi weakness, dredge milk and cure malnutrition. "

⑦ "Hunan medicine annals": "clearing heat, astringency, dispelling wind, killing insects. Treat hernia. "

⑧ "Mindong Materia Medica": "moistening lung, nourishing Yin, benefiting liver, nourishing kidney. It can cure night blindness, night sweat, spermatorrhea and lumbago. "

[usage and dosage] oral administration: decoction, 0.5-1 Liang (fresh 1-2 Liang); or stewed meat. External use: fumigation or tamping with boiling water.

[prescription selection] ① treatment of spermatorrhea: one or two antipyretic herbs. Stewed pork, once in the morning and once in the evening. (Guizhou folk medicine)

② Treatment of kidney deficiency enuresis: Night closed, bamboo shoots, black beans, glutinous rice, pepper. Stewed pork belly suit. (records of Sichuan Traditional Chinese Medicine)

③ Treatment of diabetes: cut leaf iron broom fresh whole grass four Liang, drink add chicken, water stew service; another with iron amaranth dry whole grass one to two liang, water fried instead of tea. (Fujian Chinese herbal medicine)

④ Treatment of large and small abortion: close the door at night, cook green shell duck eggs. (records of Sichuan Traditional Chinese Medicine)

⑤ Treatment of chronic turbidity: Night closed, dream flower root, white moss skin. Stewed pork suit. (records of Sichuan Traditional Chinese Medicine)

⑥ Cure ulcer disease: black medicine three money, cut leaf iron broom three money, Agrimonia one or two. Fried in water, one dose a day, twice a day. Avoid spicy food. (selected materials for investigation of unilateral and verified prescriptions)

⑦ Five iron brooms can be used to treat stomachache. Take it in water. (commonly used Chinese herbal medicine in Shanghai)

⑧ Treatment of labor injury: one to two iron broomsticks. Fried in water and washed with honey. (Zhejiang folk herbal medicine)

⑨ Cure neurasthenia, leucorrhea too much: iron broom whole grass or root one or two. Take it in water. (Zhejiang folk herbal medicine)

⑩ Treatment of children's yellow complexion: dry a money, fish loach string root three money, antipyretic grass three money. All the above medicines are taken with dry rice water. Three times a day, take one or two drops at a time. (Guizhou folk medicine)

(11) treatment of malnutrition and diarrhea: the whole grass of iron broom, fried in water. (Hunan medical records)

(12) treatment of infantile malnutrition: close for three to five dollars on a fresh night. Stew with chicken liver without water for three to five times.

Treatment of pediatric hernia: qianliguang dry whole grass five to nine money, four liang of lean pork. Take it in water.

(14) treatment of dysentery: close the door three to four Liang in fresh night. Take it in water. (12) the following formula is Fujian folk herbal medicine.)

Treatment of anal prolapse: three liang of dry antipyretic grass. Stewed pig dirty head half Jin service, every morning and evening each service, each time two, even soup service. (Guizhou folk medicine)

(16) treatment of postpartum joint gout: four liang of fresh night closed door, eight liang of pig feet. Four Liang wine, drink and add water to fry. (Fujian folk herbal medicine)

Treatment of vision loss: eight liang of the whole grass at night, twelve and five yuan of plantain grass, five yuan of Celosia argentea, five yuan of geranium, five yuan of angelica, one or two yuan of wolfberry root, dodder seed and Ligustrum lucidum. Take it by frying. (manual of Chinese herbal medicine by Su Yi)

(18) treatment of liver heat, red swelling and pain. Add rock sugar, boil water, stew for one hour, take after dinner, twice a day. (Fujian folk herbal medicine)

(19) treatment of injury caused by urinary obstruction, abdominal pain: Night closed one or two, Centella five money. Drink water to fry, take twice a day. (Fujian folk herbal medicine)

⒇ treatment of knife injuries: reduce fever, chew, apply knife wounds. (Guizhou folk medicine)

(21) treatment of breast swelling and pain: close the door at night, wash and rot, stir fry with wine, pack swelling and pain. (Sichuan Traditional Chinese Medicine Guide)

(22) treatment of dog bites, snake and insect injuries, wind heat, dampness and poison: five to one or two yuan for an iron broom. Fry in water, take orally and wash out. (Hunan medical records)

[clinical application] ① treatment of chronic tracheitis

Use 2 liang of yeguanquan grass (3 liang of fresh grass), add water to fry for 1-2 hours, concentrate to 100 ml, add appropriate amount of sugar. 50 ml each time, twice a day. 10 days is a course of treatment. According to the patient's condition, the drug was taken continuously for 3-4 courses, and the drug was stopped for 5 days between the two courses. 427 cases were treated. The total effective rate (including clinical recovery or short-term control, marked effect and improvement) was more than 80%. It was effective for simple residual asthmatic type, and the effect of mild disease was slightly better than that of severe disease. The effect of closing the door at night on relieving cough and resolving phlegm is more significant, followed by relieving asthma; about 40% of the patients are in the treatment

Chinese PinYin : Ye Guan Men