Kissing

(Ben Jing)

[synonyms] Ye Ge (Ben Jing), Qin Gouxi, Du Gen (Wu Pu Ben Cao), ye Ge, hu man Cao (Southern grass like), Huang Ye Ge (Qian Jin Fang), Chu Xin (Shu Ben Cao), Wen Mang, duanchang Cao (Mengxi Bi tan), LAN Chang Cao (compendium), Chaoyang Cao (preparation of raw herbs), Da Cha Yao, Hu Lang Cao (Lingnan herbs collection record), Suo Ge Cao (Fujian herbs collection record) The main toxic plants in the south of China are kuwangong, hebanyao, falangteng, dacha vine, dachangye, dacha vine, dachangye, dacha vine, dacha vine, dacha tea, dacha vine, yangdaigui and Suoqi.

[source] it is the whole plant of Melastomataceae.

[plant morphology] hu man Teng

Evergreen Liana with smooth branches. Leaves opposite, ovate oblong to ovate lanceolate, 7-12 cm long, 2-5.5 cm wide, apex acuminate, base cuneate or suborbicular, entire; petiole 1.2 cm long. Cymes 3-branched, terminal or axillary; flowers small, yellow; bracts 2, small and narrow; sepals 5, separated, ca. 3 mm long; corolla funnel-shaped, apex 5-lobed, 1-1.6 cm long, with pale red spots, lobes ovate, apex pointed, shorter than tube; stamens 5; ovary superior, 2-locular, style filiform, stigma 4-lobed. Capsule ovoid elliptic, 10-14 mm long, 6-8 mm in diameter, divided into two 2-lobed petals. Seeds numerous, winged. The flowering period is from August to November. The fruit period is from December to February next year.

Born on sunny hillside, roadside grass or shrub. It is distributed in Zhejiang, Fujian, Guangdong, Guangxi, Guizhou and Yunnan.

The root of this plant (big tea herb root) is also used for medicine. Please refer to the special section for details.

[collection] all year round.

[chemical constituents] the roots, stems and leaves contain alkaloids: gelsemin, Yin, Mao, a, C and Chen. Among them, the content of gelsemin is the highest. Gelsemin is highly toxic and is the most important effective component. In addition, it was reported that gelsemin a, Fructus, Fructus Mao, D and E were found in the roots of gelsemin from Fujian, while gelsemin a, Fructus Mao, D and E were found in the roots of gelsemin from Guangdong.

[pharmacological action] the root, stem and leaf are highly toxic. In the 1930s, Chinese scholars had a detailed study on the chemistry and pharmacology of Camellia sinensis and Camellia sinensis. The main toxic components of Gelsemium are gelsemium, gelsemium Yin and gelsemium Mao. The minimum lethal dose of coumarin Yin to rabbits was 0.8 mg / kg. The main symptoms of poisoning were respiratory paralysis, dyspnea in mild cases and respiratory arrest in severe cases. After the death dose of gelsemin B caused the animals to stop breathing, the heart continued to beat. The inhibition of respiration was not central. Neither brain removal nor vagotomy affected the inhibition of respiration. Neither alkali nor picrotoxin had significant rescue effect. On the other hand, it has no direct paralyzing effect on peripheral neuromuscular apparatus. Gelsemin B can inhibit and stop the rhythmic contraction of isolated diaphragm, which is the same as that of in situ diaphragm. Direct stimulation of phrenic nerve after respiratory arrest can still cause diaphragm contraction. In addition, after poisoning, all animals showed ptosis of eyelids, drooping head, soft feet and weakness of whole body muscles, so it is speculated that its role is in spinal cord motor neuron paralysis.

The effective dose of gelsemin a was similar to the toxic dose. However, it has also been reported that when combined with aspirin, the analgesic effect is enhanced, which is better than that when used alone. It is also said that it has good clinical effect. The recommended dose is 300-500 mg of aspirin and 0.5-2 mg of gelsemin a.

Gelsemin B had no significant effect on circulatory system. It can be antagonized by barium chloride and epinephrine, but atropine has no effect. When the dosage is small, the pulse speed up is caused by the decrease of vagal tension, and the blood pressure still has no obvious change; when the dosage is large, the heart is inhibited and the blood pressure drops, and the blood pressure drops mainly due to the inhibition of the heart, and partly due to the decrease of the excitability of the vascular motor center; the toxic dosage can cause ventricular fibrillation. Gelsemin a can block the hypotensive response induced by electrical stimulation of cardiac vagus nerve or injection of acetylcholine. It has a weak serotonin like effect and can enhance the pressor effect of epinephrine. In dogs and rabbits, the small intestine and uterus were slightly excited and a large amount of inhibition, which was the direct effect on smooth muscle. Domestic gelsemium also showed inhibitory effect on smooth muscle, and antagonized with acetylcholine and barium chloride. Gelsemin a has no curare like effect, no ganglion paralysis and no central sedative effect. Domestic gelsemium and gelsemin a have the effect of dilating pupil.

In clinic, it can be used to treat neuralgia, especially trigeminal neuralgia, and its tincture can also be used to treat acute poliomyelitis. Because the therapeutic dose is very close to the toxic dose, it is necessary to be very careful and closely observed, especially the breathing condition. It can be used locally to dilate the pupil, but it is irritating, so its application is limited.

It's hard, warm and poisonous.

① Ben Jing: "Xin, Wen. "

② Wu Pu's materia medica: "Lei Gong: poisonous. "

③ Bielu: "there is great poison. "

④ "Bitter, cold and poisonous" is recorded in the collection of herbs in the south of the five ridges. "

⑤ "Guangxi medicine plant atlas" says: "it's bitter, but it's poisonous. "

Functions and indications: dispel wind, attack poison, detumescence and relieve pain. It can treat scabies, eczema, rash, carbuncle, sore, traumatic injury, rheumatic arthralgia and neuralgia.

① "Ben Jing" says: "it is the main cause of golden sores, evil wind in the breast, cough against the upper Qi and edema. "

② Bielu: "broken hundred accumulation, foot and knee arthralgia, limb contracture, sores and scabies. "

③ Shu materia medica: "the main throat obstruction, pharyngeal congestion, voice change, cough adverse gas, warm.". "

④ "Preparation of the nature of raw herbal medicine": dispelling wind and poison, washing scabies. "

⑤ "This Jing meets the original": "purple person breaks blood accumulation, green person breaks phlegm accumulation. "

⑥ "No matter the roots, stems and leaves, it can disperse wind and heat toxin, and wash scabies and tinea by boiling water. Where the willow poison, chancre, to decoct juice, soak two or three times. "

⑦ "Guangxi medicine Zhi Tu Zhi": "smash external application to treat bruise, blood stasis, traumatic bleeding, syphilis, sores, wind arthralgia; make ointment to eliminate tumor. "

⑧ Guangzhou Air Force's "manual of commonly used Chinese herbal medicine": "attack poison and extract poison, kill insects, relieve itching, disperse blood stasis and relieve pain. Treatment of skin eczema, traumatic injury, closed fracture. "

[usage and dosage] external use: tamping or grinding, boiling, washing or smoking.

[should not] this product is highly toxic. It is only for external use, and should not be taken orally.

Ben Cao Jing Ji Zhu: "to do it is evil. "

[selection] 1. Treatment of scabies: two cents each for Saussurea esculenta, kufan, Maqianzi and shetui, four cents each for Meipian, and one and five cents each. They are fine powder, melted with wax oil and pasted with ointment. (Lingnan herbal medicine)

② Treatment of scrofula: heartbroken grass root, red old cassava, two taste discretion. A total of mash, with acid fried for an hour, waiting for cold compress on the affected area, for three days. (Lingnan herbal medicine)

③ Cure carbuncle sore swollen poison: unripe cut bowel grass four Liang, yellow sugar five money. Tamp the affected area together. (illustrated records of medicinal plants in Guangxi)

④ Treatment of carbuncle and gangrene: after drying in the sun and grinding in the end, mix with vaseline to make ointment for the affected area.

⑤ Ye Yuannian's sore: a kilo of fresh tea medicine, fried water to wash the affected area, wash several times a day, after washing, put a sore on the medicine leaf.

⑥ Treatment of gangrene: big tea leaves. Two flavor mash, paste refers to the third section, there is pus that ulcers, no pus that disappear. (4) Lingnan herbal medicine annals

⑦ Treatment of rheumatoid arthritis pain: dry heartbroken grass one or two, two money, one money. Study the coarse powder and burn the paper to smoke the affected area. (illustrated records of medicinal plants in Guangxi)

⑧ Treatment of knife wound: smash the heartbroken grass and apply it to the wound. (Lingnan herbal medicine)

[poisoning] this product is highly toxic, and root and leaf (especially tender leaf) are the most toxic. It can easily lead to poisoning or even death. The main manifestations of poisoning: ① neuromuscular symptoms: vertigo, vague speech, muscle weakness, dysphagia, respiratory muscle paralysis, peripheral nerve paralysis, ataxia, coma, etc.; ② eye symptoms: diplopia, vision loss, blepharoptosis, mydriasis, etc.; ③ digestive system symptoms: burning pain in mouth and throat, nausea, vomiting, abdominal pain, diarrhea, constipation, abdominal distension, etc.; ④ circulation And respiratory symptoms: early slow heartbeat, later accelerated, dyspnea, respiratory paralysis, collapse, etc. The speed of symptoms is related to the method of taking. The symptoms often appeared immediately after taking root decoction or fresh buds. The symptoms appeared slowly after taking root decoction, and appeared only 2 hours later. Rescue methods: gastric lavage, emesis, catharsis, infusion and symptomatic treatment. Traditional Chinese medicine can be taken with Sanhuang Decoction (Radix Scutellariae, Radix Scutellariae, Radix Scutellariae), water spinach juice or mashed with tea oil, mashed with leaves and juiced with yellow sugar, and Radix Polygoni Multiflori with Maogen decoction. Folk experience, with fresh sheep blood by hot perfusion rescue, clinical confirmed that there is effect.

Chinese PinYin : Gou Wen