Lonicera japonica Thunb

Lonicera japonica Thunb

(notes to the classic of Materia Medica)

[synonyms] laowenxu, jinchaigu, Da Xue Li, shuiyangteng, qianjinteng (Su Shen Liang Fang), yuanyangcao (Mo Zhuang man Lu), Lu Si Teng (Lu? Yan Ben Cao), Lonicera japonica (key points of syndrome and treatment), zuoguan Teng (Yu Jushi selected Qi Fang), renhancao (Hong Shi Ji Fang), Tonglingcao, mitongteng (TU Su Ben Cao), honeysuckle (Dan Xi Xin Fa), Jinyin (Yinyin) Rattan (Qiankun business secret), honeysuckle (Diannan materia medica), sweet rattan (materia medica), Youzhuan rattan (classified herbal medicine), dextran rattan (Guizhou folk medicine Collection), erhuayang and yinhuayang (Henan traditional Chinese medicine manual).

[source] stems and leaves of Lonicera japonica.

[plant morphology] Lonicera japonica Thunb

Perennial semi evergreen twining shrubs, up to 9 m high. The stem is hollow and the young branches are densely pubescent. Leaves opposite; petiole 4-10 mm long, densely pubescent; leaf blade ovate, or long ovate, 2.5-8 cm long, 1-5.5 cm wide, apex short, rarely obtuse, base rounded or nearly cordate, entire, both sides and margin pubescent. Flowers axillary in pairs; pedicels densely pubescent; bracts 2, leaflike, broadly ovate; bracts about 1 mm long; calyx short, 5-lobed, lobes triangular, apex acute; corolla zygomorphic, 5 cm long, lip shaped, upper lip 4-lobed, corolla tube slender, about as long as lip, outside pubescent, flowers initially white, 2-3 days later golden yellow; stamens 5, inserted The style is slender and the stamens extend out of the corolla. Berries globose, ca. 6 mm in diam., black when ripe. The flowering period is from May to July. The fruit period is from July to October.

It is also cultivated in the wild. It is distributed in Liaoning, Hebei, Henan, Shandong, Anhui, Jiangsu, Zhejiang, Fujian, Guangdong, Guangxi, Jiangxi, Hunan, Hubei, Sichuan, Guizhou, Yunnan, Shaanxi, Gansu, etc.

The flower bud (honeysuckle) and fruit (yinhuazi) of this plant are also used for medicine. Please refer to the special section for details.

[collection] the stems and vines with leaves were cut in autumn and winter, tied into small bundles and dried in the sun.

[medicinal material] the dry stem is slender and cylindrical, with a diameter of 1.5-6 mm. The surface is dark red or gray brown, with fine hairs, especially the tender branches. The skin is easy to peel off, often tearing into fibrous shape. On the stem often has the ellipse, the green yellow leaf, many broken incomplete. It is hard and brittle, with grayish white or yellowish white cross section and a gap in the central medulla. Weak Qi and weak taste. The skin with jujube red, tender and leafy is the best.

It is mainly produced in Zhejiang, Sichuan, Jiangsu, Henan, Shaanxi, Shandong, Guangxi, Hunan and other places. In addition, it is also produced in Anhui, Gansu, Hubei, Jiangxi, Fujian, Shanxi, Yunnan, Liaoning, Hebei and other places.

[chemical constituents] the leaves contain flavonoids such as luteolin-7-rhamnoglucoside and luteolin. The stem contains tannins and alkaloids.

[pharmacological action] luteolin has antispasmodic effect on smooth muscle (rabbit's small intestine), but not as good as papaverine, and has mild diuretic effect (increasing the excretion of sodium chloride).

Luteolin can cause thymus atrophy in young rats (25-28 days after birth), which is related to pituitary adrenal system and can be used to explain its anti-inflammatory effect. Luteolin can inhibit the growth of Staphylococcus and Bacillus subtilis in vitro at the concentration of 1:350000

[processing] remove impurities, soak in water, moisten, slice and dry.

Sweet and cold.

① Bielu: "sweet, warm, nontoxic. "

② "On medicinal properties": "taste is pungent. "

③ Materia medica: Xiao Han. "

④ "Bencao Zaixin" says: "it tastes sweet and bitter, and its nature is slightly cold. "

[meridian tropism] entering heart and lung meridians.

① Yaoyaofenji: "entering the lung meridian. "

② New materia medica: "entering the heart and lung meridians. "

Functions and indications: clearing away heat, detoxifying and dredging collaterals. It is used to treat febrile diseases, fever, blood dysentery, infectious hepatitis, carbuncle swelling, sores and pain of muscles and bones.

① Bielu: "the main cold warm-up swelling. "

② Tao Hongjing: "boiling juice to make wine, tonifying deficiency and curing wind. "

③ "Theory of medicinal properties": "the main abdominal distension full, can soil gas under?"?. "

④ Materia medica notes: "it is mainly heat toxin, blood dysentery and water dysentery. "

⑤ "Lvyan Materia Medica": "treating muscle and bone pain. "

⑥ "Diannan Materia Medica": "it can widen the middle and lower Qi, eliminate phlegm, dispel wind and heat, and clear throat heat pain. "

⑦ "Gangmu": "it can cure all kinds of wind, dampness, swelling and poisons, carbuncle, gangrene, scabies, bayberry, heat dissipation and detoxification. "

⑧ "Materia medica re new": "treatment of heart deficiency, fire, Buqi Kuanzhong, cough, carbuncle flaccidity..

⑨ "Nanjing folk herbs": "stems, leaves and flowers have curative effect on eye inflammation. "

⑩ Guizhou folk medicine collection: "Ye: external application for treating knife wounds. "

(11) Guangzhou army's "manual of commonly used Chinese herbal medicine": "treating leg pain due to damp heat. "

Usage: oral administration: 1-0.3 pills or powder. External use: fumigation and washing with boiling water, paste boiling or dressing with grinding powder.

[selection of prescriptions] ① for the treatment of exogenous diseases, fever and thirst, or limb soreness at the four seasons: honeysuckle vine (with leaves or flowers, dry) or two (fresh or three Liang). Fried soup instead of tea. (Quanzhou materia medica)

② Treatment of heat toxic blood dysentery: honeysuckle vine thick fried ridge. (Sheng Hui Fang)

③ Treatment of carbuncle, carbuncle, milk carbuncle, nameless swelling and pain, hate cold and strong heat, like typhoid: honeysuckle (to stem), astragalus (to Lu) each five Liang, angelica 12 money, licorice (fried) eight Liang. For the fine powder, each take two money, wine one and a half, fried to a cup, if the disease in the food after the service, the disease in the next food before the service, less into the second service; residue external application. If the pus is not formed, it will dissipate internally, and if the pus is formed, it will ulcerate. (kufang's magic effect Tuoli powder)

④ Cure all carbuncle: honeysuckle vine (raw take) five Liang, big licorice festival one or two. Add two bowls of water, fry a bowl, add a bowl of ashless good wine, fry several times, remove dross, take three times, one day and one night use up, sick day and night two doses, to the degree of urination and defecation; another use a handful of honeysuckle vine rotten research, a little wine around. (essence of surgery honeysuckle)

⑤ Cure all kinds of swelling and pain, golden blade wound sores, sores: gold and silver vine four Liang, magnet three money, sesame oil a Jin. Boil dry to dross, into the yellow pill eight Liang, to boil until the water does not spread, as usual. (honeysuckle cream in business secrets of heaven and earth)

⑥ Cure evil sores is not cured: left entwined vine. Mash, add realgar five minutes, water two liters, fry it in earthen pot, seal seven times with paper, pierce a hole, wait for the gas to come out, and smoke it with sore to the hole for three hours. It can also treat carbuncle caused by light powder. (Yu Jushi's selection of strange prescriptions)

⑦ Cure sore long into leakage: Honeysuckle soak wine often take. (key to syndrome differentiation and treatment)

⑧ Treatment of rheumatoid arthritis: Honeysuckle rattan one or two, thin grass four money, chicken blood rattan five money, old crane grass five money, white Myrtle four money, decoction. (Shandong traditional Chinese Medicine)

⑨ Cure poison grass poisoning: fresh honeysuckle tender stems and leaves appropriate amount, wash with cold boiled water, chew down. (commonly used Chinese herbal medicine in Shanghai)

[clinical application] ① treatment of infectious hepatitis

Take 2 liang of honeysuckle vine, add 1000 ml of water, fry to 400 ml, take it separately in the morning and evening. 15 days is a course of treatment, with an interval of 1-3 days. 22 cases were treated, of which 12 cases had normal liver function, 6 cases had obvious improvement of liver function and 4 cases had no obvious change of symptoms and signs.

② Treatment of bacillary dysentery and enteritis

Cut 100 grams of honeysuckle vine into pieces, put it in a earthen jar, add 200 ml of water, put it for 12 hours, decoct it with slow fire for 3 hours, add proper amount of distilled water to make it 100 ml, and then filter. Take 1.6-2.4 ml per kilogram of body weight every day. Increase or decrease according to the severity of the disease. Generally, take 20ml for the first time, once every 4 hours; after the symptoms improve, change to 20ml, 4 times a day, until 2 days after the diarrhea stops. 60 cases of bacillary dysentery and 90 cases of enteritis were treated, and good results were obtained in 146 cases except 4 cases who did not take the medicine for 1-2 days. The average disappearance time of symptoms was: abdominal pain for 3 days, fever for 2 days, diarrhea for 2 days, stool formation for 4.4 days. No adverse reactions were found. Another useful honeysuckle 1.5 Liang, twice a day, while honeysuckle 5 money Decoction retention enema, once a day. 7 days for a course of treatment. Among 167 cases of acute bacillary dysentery, 131 cases (78.44%) were cured after one course of treatment, and 36 cases were ineffective. The average days of fever abatement, stool frequency, stool characteristics and microscopic examination returned to normal were 5.6, 4.5 and 4.9 days, respectively. The days of bacterial culture turned negative were mostly about 3 days. The negative conversion rate of intestinal lesions in colonoscopy within 10 days was 84.6% for non ulcer type and 80% for ulcer type. 80 cases of chronic bacillary dysentery were treated, and the cure rate was 73.9%. The fever cases returned to normal in an average of 1.5 days, the stool frequency, character and microscopic examination returned to normal in an average of 5.5 and 4.6 days, and the bacterial culture turned to negative in an average of 3.7 days; colonoscopy: 24 cases of non ulcer type returned to normal, 38 cases of ulcer type recovered within 10 days, accounting for 84.2%.

In addition, it is effective to treat appendicitis by Decoction of Lonicera japonica Thunb. 4 or other drugs combined with syndrome differentiation.

[discussion by famous experts] 1. Compendium: "the functions of stems, leaves and flowers of Lonicera japonica are the same. In the past, people called it an important medicine for the treatment of wind, distension and dysentery, but later generations did not know how to use it. Later generations called it an important medicine for the treatment of swelling, toxin and sores, but people did not mention it in the past. They knew the principles of ancient and modern times. According to Chen Ziming's "Essentials of surgery", honeysuckle wine is more effective in treating carbuncle and gangrene on the back of the hair, and it should be taken at the first time. Hong Mai and Shen Kuo have detailed descriptions. "

② "True biography of Medicine:" every time I use honeysuckle, there are many different people

Chinese PinYin : Ren Dong Teng