Macleaya

Macleaya

(notes on materia medica)

[synonyms] Luohui (Youyang Zazu), haochangcao (Clarke grass), bleehui (plant name and reality) and Jiangan (Hunan wild plants), haochangqing (local pesticide records), gundilong (Guangxi Traditional Chinese veterinary medicine Zha), shanhaotong, shanmagu (local pesticide records of China), houhoubaozhu, kongyaocao, jiaoluochui, haojiaojiaodouzhu, flax tube (Zhejiang pesticide records), etc Qian three (Guangxi Chinese medicine record), Shan fire tube (pesticide plant manual), mountain Wutong ("Hangzhou Zhi Zhi Zhi"), through the sea, bubble beads, edge heaven Artemisia, all rhubarb ("Hunan medicine"), the earth tyrant ("Jiangxi folk herbal prescription"), tung tree ("Jiangxi medicine" (7):3711966).

[source] it is the whole grass with roots of Macleaya, a Papaveraceae plant.

Macleaya cordata

Perennial herbs, 1-2 meters high, all with white powder, yellow juice outflow after breaking. Stem cylindrical, hollow, green, sometimes reddish purple. Single leaf alternate, broad ovate, 15-30 cm long, 12-25 cm wide, 5-7 or 9-lobed, lobes with irregular wavy teeth, green above, smooth below, white, with dense hairs; petiole 5-12 cm long, base expanded and clasping. Panicle terminal or axillary, calyx 2, white, oblanceolate, margin membranous, caducous; apetalous: stamens numerous, filaments thin and flat; pistil 1, ovary obovate, flat, style short, stigma 2-lobed. Capsule pendulous, obovate, oblong, ca. 2 cm long, ca. 5 mm wide, flat, red, surface with white powder, style persistent. Seeds 4-6; oblong, brown and glossy. The flowering period is from June to July. The fruit period is from August to November.

It is distributed in the middle and lower reaches of the Yangtze River Basin.

[collection] harvest from May to October.

[chemical constituents] the roots contain sanguinarine, chelerythrine and maclealline. In addition, protoopioid, α - allocryptopinine, oxysanguinarine, B-Base and C-base were separated. Protoopioid, α - allocryptopinine and another a-Base were isolated from the whole plant.

[pharmacological action] 1

The three alkaloids in Macleaya cordata have nematicidal effect and also have inhibitory effect on some bacteria and fungi.

② Maggot killing effect

The results showed that Macleaya cordata had maggot killing effect and could inhibit the hatching of fly eggs; the leaf and pericarp had the strongest maggot killing effect, followed by the stem, and the root had the weakest maggot killing effect.

[toxicity] Pleurotus ostreatus contains many kinds of alkaloids, which are quite toxic. In the literature, there have been many reports of poisoning and even death after oral or intramuscular injection, mainly causing acute cardiogenic cerebral ischemia syndrome. Animal experiments also showed that boluohui injection could cause T wave inversion, multiple ventricular premature contractions and transient paroxysmal tachycardia. Atropine had antagonistic effect.

It's hard, warm and poisonous.

① "There is a lot of poison in the collection of Materia Medica. "

② Sichuan Traditional Chinese medicine annals: "bitter, pungent, warm, and poisonous. "

③ "Hunan medicine annals": "pungent and astringent, cold, small poison. "

[function indications] detumescence, detoxification, insecticidal. It is used to treat finger sores, abscesses, acute tonsillitis, otitis media, trichomonal vaginitis, lower limb ulcers, scalds and tinea.

① Jiangxi folk herbal medicine: "for the treatment of acne, ringworm and baldness, soak the leaves in vinegar for seven or eight days, apply the pestle to the affected area, and change every day. "

② "Guangxi Traditional Chinese medicine annals": "external treatment of Dieda. "

③ "Hunan medicine records": "dispelling wind and detoxification, promoting qi and detumescence, killing insects. "

[usage and dosage] external use: tamping; fumigating with boiling water or mixing with grinding powder.

[taboo] this product is toxic, and should be taken with caution.

[prescription selection] 1. For the treatment of malignant sores, gall roots, tumors, polyps, vitiligo, poisonous insects, stream poison, those who have been treated with "Shang" and "Sheng" sores and fistulas: boluohui, baizhangqing, jisanghui, etc. For the last application. (notes on materia medica)

② Zhizhi: Yibo falls back to the root skin, falls to the ground, arches the root, etc. Add a little salt, mash with strong tea juice, apply to the affected area. (prescription of Jiangxi folk herbal medicine) a handful of tung tree No.2 (with stem and leaf) is fried and smoked for about 15 minutes, and then the fried leaves are pasted on the affected fingers, two to three times a day. Early inflammations, such repeated fumigation, external paste three to six times. If it has been suppurated, it must be cut to discharge the pus, which is not suitable for this drug. (Jiangxi medicine (7): 3711966)

③ Treatment of acne: the whole grass of Macleaya cordata, burning, grinding very fine powder, sprinkle in the sore, or use sesame oil to wipe, or with pig oil to pound and paste. (prescription of Jiangxi folk herbal medicine)

④ Treatment of lower limb ulcers: yiboluohui Decoction and water washing; another two leaves, mixed with white sugar, steamed in the pot for a few minutes, take out the affected part, change once a day. Erbo Luohui (fresh root) 2 kg, fry thick juice, adjust candle oil, spread around the sore, and wrap it with gauze.

Otitis media: Baijiu Hui and the end of liquor research, clarified and sprinkled with wick.

⑥ Treatment of tinea corporis (mangrove): first shaving, and then back to two, alum one or two, fried and washed, once a day, a total of seven days.

⑦ Water, fire burns: Bo Luo back to the end of the root research, cotton seed oil transfer liniment. (4) herbal medicine manual of Jiangxi Province

⑧ Treatment of centipede, wasp bite: take fresh Macleaya back to the stem, broken, yellow juice outflow, with juice on the affected area. (prescription of Jiangxi folk herbal medicine)

[clinical application] 1

They were injected intramuscularly with boluohui injection, 2 ml each time, 2-4 times a day for adults and 0.5-1.5 ml each time, 2 times a day for children. It has been used in more than 300 patients with lobar pneumonia, infantile pneumonia, acute tonsillitis, upper fever, bronchopneumonia, subauritis, acute appendicitis, deep abscess, biliary ascariasis, cholecystitis, trauma, lower leg ulcer, vasculitis, incomplete intestinal obstruction, puerperal fever, various small and medium-sized surgery, and more than 90% of them can prevent or control infection. According to the results of drug sensitivity test, Macleaya cordata is highly sensitive to Staphylococcus aureus, Staphylococcus albicans, Shigella dysentery, proteus, typhoid, Shigella sonnei, Bacillus anthracis, Shigella flexneri and Streptococcus viridis; moderately sensitive to Shigella baumannii, Escherichia coli and Escherichia coli like; not sensitive to Pseudomonas aeruginosa.

② Treatment of trichomonal vaginitis

Cut up the stems and leaves of fresh trumpet pole (Macleaya cordata) and add water to boil it into an extract containing 25g crude drug per ml. First, use 1:5000 potassium permanganate solution (50% horn rod solution for severe cases) 300-500 ml to flush the vagina, and then use cotton swab to dip medicine to repeatedly wipe the vaginal wall for 2-3 times, or detain vaginal cotton plug containing medicine. The course of treatment was 7-10 days. After 3 days of treatment, specimens were taken for microscopic examination to observe the curative effect. The best time of treatment is after the end of menstrual period. General 3 courses of treatment can cure. A total of 132 patients were treated. After a course of treatment, all the symptoms disappeared and all the vaginal secretions turned negative by microscopic examination. According to the microscopic observation, the Trichomonas died immediately after the extract of horn pole was dripped on the glass slide containing the Trichomonas, while the Trichomonas was still active 2 hours after CARBARSONE and metronidazole were dripped. It is proved that the extract of bugle pole is a kind of drug with strong trichomonacidal effect.

Chinese PinYin : Bo Luo Hui