Zhang Xu

Zhang Xu

Zhang Xu, born in August 1961 in Yixing, Jiangsu Province, is a neuroscientist and academician of the Chinese Academy of Sciences. He is now a researcher of Shanghai Institute of life sciences, Chinese Academy of Sciences and vice president of Shanghai Branch of Chinese Academy of Sciences.

He graduated from the Fourth Military Medical University in 1985 and received a doctor's degree from Karolinska Medical College in Sweden in 1994. On December 7, 2015, he was elected academician of the Chinese Academy of Sciences.

Zhang Xu has long been engaged in the study of molecular cellular biological mechanism of nervous system diseases.

Character experience

From September 1985 to April 1987, he was a teaching assistant in the Department of neurobiology, Fourth Military Medical University.

From May 1987 to January 1988, he was a visiting scholar in the Department of ultrastructure, University of Stockholm, Sweden.

From February 1988 to September 1990, he was a teaching assistant in the Department of neurobiology, Fourth Military Medical University.

From October 1990 to July 1994, he was a doctoral candidate in neuroscience Department of Karolinska Medical College, Sweden.

From August 1994 to November 1994, lecturer, Institute of neuroscience, Fourth Military Medical University.

From December 1994 to November 1997, associate professor, Institute of neuroscience, Fourth Military Medical University.

From December 1997 to November 1999, Professor, doctoral supervisor, Institute of neuroscience, Fourth Military Medical University.

From November 1999 to July 2010, he was the project leader and researcher of Institute of neuroscience, Chinese Academy of Sciences, and vice president of Shanghai Academy of life sciences

From July 2010 to present, he is the research group leader and researcher of Institute of neuroscience, Chinese Academy of Sciences.

On December 7, 2015, he was elected academician of the Chinese Academy of Sciences.

Main achievements

Achievements in scientific research

He has been engaged in the research of molecular and cellular biological mechanism of nervous system diseases for a long time. We systematically studied the gene expression profiles of dorsal root ganglion and spinal cord in chronic pain, and found new pain information regulation systems such as endogenous sodium potassium pump agonists, which provided a new theoretical basis for clinical analgesia and drug research and development. The interaction between opioid receptor subtypes in nociceptive neurons and the correlation between opioid receptor subtypes and morphine tolerance were found, which expanded the research direction of receptor complex function and drugs. It is found that fibroblast growth factor 13 (fgf13) regulates the development of neurons and brain by stabilizing microtubules, and elucidates the mechanism of mental retardation caused by fgf13 gene defect.

First prize of science and technology progress of PLA in 1992 (third author), General Logistics Department of PLA.

In 1995, national fund for Distinguished Young Scholars (Class A), National Natural Science Foundation of China.

First prize of science and technology progress of PLA in 1996 (first author), General Logistics Department of PLA.

2004 Shanghai Science and technology progress second prize, Shanghai Municipal People's government.

2005 he Liang He Li Foundation Science and Technology Progress Award - Medical Pharmacy award, he Liang He Li foundation.

2006 Asia Outstanding Young Scientist Award, Lilly Pharmaceutical Group.

Honorary recognition

In 1998, the Sixth China Youth Science and technology award was awarded by the Organization Department of the CPC Central Committee, the Ministry of personnel and the China Association for science and technology.

2003 innovative research group, National Natural Science Foundation of China.

1998 National Fund for Distinguished Young Scholars (category C), National Natural Science Foundation of China.

2006 Shanghai Natural Science peony award.

On December 7, 2015, he was elected academician of the Chinese Academy of Sciences.

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Chinese PinYin : Zhang Xu