Yan Lunan

Yan Lunan

Yan Lunan, male, was born in Shaoxing, Zhejiang Province in July 1944. He graduated from Chongqing Medical University in 1967. He successively obtained master's and doctor's degrees from Sichuan University (formerly West China Medical University), professor and doctoral supervisor.

Life of the characters

Director of Department of general surgery, West China Hospital of Sichuan University, director of liver transplantation center, director of hepatobiliary pancreatic research department. in 1987, he came back from studying in Japan and engaged in liver surgery and gene therapy of liver cancer. It is the first to establish a number of indicators to monitor liver energy metabolism in China, which can be used to predict liver reserve function in clinic, and greatly improve the resection rate and safety of liver cancer surgery. Over the past 20 years, more than 6000 cases of primary liver cancer have been operated on. The resection rate is 70.7%, the operative mortality is reduced to 0.74%, and the overall 5-year survival rate is 70.2%. We have created the technique of half hepatic blood flow occlusion and ligation to cut off the liver. We have carried out new and complex operations such as central hepatectomy, caudate lobectomy, lobectomy under extracorporeal bypass, resection of portal vein tumor thrombus, simultaneous lobectomy and splenectomy. in 1994, we began to study the animal experiment of total liver transplantation and half liver transplantation, and the research of liver regeneration after hepatectomy. since 1999, we have led the implementation of clinical liver transplantation. So far, there are about 1000 cases. The 1 -, 3 -, and 5-year survival rates of benign liver diseases are 87.4%, 80.5%, and 72.7% respectively, reaching the international advanced level. living donor liver transplantation in children was carried out in 2001, and the first case of adult to adult living donor liver transplantation in China was carried out in 2002. Because the operation risk of adult to adult living donor liver transplantation is more than 10 times higher than that of child living donor liver transplantation, the operation technology is complex, the risk is high, and the requirements for hospital software and hardware are high. It is the top operation of liver transplantation, representing the comprehensive strength of a hospital. Therefore, it has only been carried out for less than 10 years in foreign countries, and only a few hospitals in China have tried a few cases. from 2001 to October 2008, nearly 200 cases of living donor liver transplantation (including more than 180 cases of adult to adult living donor liver transplantation) were carried out, which is the unit with the largest number of cases and the best effect in mainland China. In 2012, it won the title of "top 100 Chinese doctors". in recent years, he has been engaged in the research of multidrug resistance gene of liver cancer and oral targeted gene microspheres for gene therapy of liver cancer, and has been funded by the National Natural Science Foundation of China, the Doctoral Program Fund of the State Education Commission and the key project fund of the Provincial Department of health. Since 1982, he has published more than 500 scientific papers, edited 5 monographs such as liver energy metabolism and modern liver surgery, liver surgery, general surgery, modern liver transplantation and living donor liver transplantation, and participated in the compilation of 10 monographs such as "surgery: Frontier and controversy" and "surgery" for graduate students of medical colleges and universities. More than 30 doctoral students, more than 40 master students and 4 postdoctoral students have been trained. He won the third prize of national scientific and technological achievements once, the first prize of Ministry of health once, the first prize of provincial scientific and technological achievements three times and the third prize three times. In 2012, Dr. Yan Lunan won the title of "top 100 Chinese famous doctors" in liver surgery. At the same time, Wang Xuehao, Yang Guangshun, Chen Xiaoping, Chen Guihua, Wu Mengchao, Zheng Shusen, Dong Jiahong and fan Jia also won the title of "top 100 Chinese famous doctors".

Present position

Director of Department of general surgery, West China Hospital of Sichuan University, director of liver transplantation center, director of hepatobiliary pancreatic research department.

Current title

Professor of surgery, doctoral supervisor.

academic activities

Academic posts: standing member of National Surgical Society of Chinese Medical Association, deputy leader of liver transplantation group of Chinese Medical Association, chairman of Sichuan Surgical Society of Chinese Medical Association, vice chairman of national liver cancer special committee of Chinese Anti Cancer Association, director of Sichuan anti cancer association, chairman of Sichuan liver cancer special committee, and academic leader of Sichuan Province. He served as chief editor of Chinese Journal of general surgery, deputy chief editor of International Journal of hepatobiliary and pancreatic surgery (English Edition), deputy chief editor of Chinese Journal of hepatobiliary and pancreatic surgery, editorial board member of Chinese Journal of general surgery, editorial board member of hepatobiliary surgery, Chinese Journal of Practical Surgery, Chinese Journal of modern surgery, Chinese Journal of modern medicine and Chinese Journal of endoscopy Standing editorial board members, etc.

Scientific research achievements

It is the first time to create a simple and safe method of hemihepatic blood flow occlusion in liver surgery, which has been popularized to the whole country. He is engaged in the research of hepatic artery embolization and cryotherapy with radioactive 32 phosphate glass microspheres for advanced liver cancer. Combined with the advantages of chemotherapy, radiotherapy and embolization, the survival rate of advanced liver cancer is significantly improved, which creates a bright future for the treatment of advanced liver cancer. In recent years, he has been engaged in the research of multidrug resistance gene of liver cancer and oral targeted gene microspheres for gene therapy of liver cancer, and has been funded by the National Natural Science Foundation of China, the Doctoral Program Fund of the State Education Commission and the key project fund of the Provincial Department of health. At the same time, we have pioneered in the world: (1) we have pioneered the surgical method of living donor right liver transplantation combined with inferior vena cava replacement in the treatment of end-stage Budd Chiari syndrome and cirrhosis, which has solved the long-term treatment problem of end-stage Budd Chiari syndrome combined with vena cava stenosis and cirrhosis. The article has been published by the international authoritative journal of liver transplantation. ② The first double donor liver transplantation was performed in the world. The article has been published by the international authoritative journal of liver transplantation. ③ The incidence of biliary complications after living donor liver transplantation decreased from 20% - 30% to 8.7%. ④ Continuous hemofiltration combined with IVF adult to adult living donor right liver transplantation was successfully used to rescue 9 patients with fulminant liver failure and severe hepatic coma who were on the verge of death. The above four points have reached the international leading level. published more than 300 scientific research papers in domestic and foreign journals (including more than 40 SCI papers), read more than 50 papers and special reports at international and domestic academic conferences, and edited monographs such as liver energy metabolism and modern liver surgery, liver surgery (Renwei Society), general surgery, modern liver transplantation, living donor liver transplantation (Renwei Society) Five books and more than 10 monographs. More than 30 doctoral students, more than 40 master students and 6 postdoctoral students have been trained. supported by a number of National Natural Science Foundation of China, doctoral program foundation of State Education Commission and key project funds of Provincial Department of health. It has won one third prize of national science and technology achievement, one first prize of Ministry of Health Science and technology achievement, one first prize of Ministry of Education Science and technology achievement and three first prizes of provincial science and technology achievement. He was successively employed as a visiting professor by Taiwan's Kaohsiung Medical University, China Medical University, Beijing You'an Hospital of Capital Medical University and other famous universities. It is well-known and influential in international and domestic surgical circles. Baidu Encyclopedia content is shared by netizens. If you find that your data content is inaccurate or incomplete, you are welcome to use your own data service (free) to participate in the correction. Go to > > now

Chinese PinYin : Yan Lv Nan