Sun Zhiwei

Sun Zhiwei

Sun Zhiwei, mainly studies the genotoxicity and reproductive development toxicity of environmental harmful factors, including the DNA damage and molecular mechanism of heavy metals, the mutagenicity of polycyclic aromatic hydrocarbons DNA adducts, and the influence and mechanism of environmental harmful factors on fetal growth and development.

Character experience

June 1984, Bachelor of health, Bethune Medical University; July 1990, master of preventive medicine, Bethune Medical University; January 1995, doctor of Mainz University, Federal Republic of Germany; June 1997, postdoctor of Bethune Medical University; June 1984, doctor of Jilin Provincial Center for health and disease prevention; July 1990, lecturer of preventive medicine, Bethune Medical University; September 1995, associate professor of Bethune Medical University; June 1997 Professor of Bethune Medical University; executive vice president of the school of public health of Bethune Medical University from June 1996 to October 1996; dean of the school of public health of Bethune Medical University from October 1996 to June 2000; dean of the school of public health of Jilin University from September 2000 to September 2003; executive vice minister of the Department of Bethune medicine of Jilin University from September 2003 to January 2007; and Dean of the Department of Bethune medicine of Jilin University from January 2007 August 2008, Professor, School of public health, Capital Medical University. director of the society of environmental mutagens director of the Chinese Preventive Medicine Association director of the Chinese society of toxicology director of the fourth council of the Chinese Anti Cancer Association member of the public health education professional committee of the Chinese Preventive Medicine Association member of the fourth vice chairman of the health toxicology Professional Committee of the Chinese Preventive Medicine Association chairman designate of the fifth Health Toxicology Professional Committee of the Chinese Preventive Medicine Association member of the Chinese Medical Association Member of the higher medical education professional committee of China Association of Environmental Sciences, member of the environmental medicine professional committee of China Association of Environmental Sciences, member of the evaluation committee of the Chinese medical science and technology award, health food evaluation expert of the State Food and drug administration, environmental and health field expert of the State Environmental protection administration, evaluation expert of the science and technology progress award of the Ministry of education, member of the health related products evaluation expert committee of the Ministry of health Peer review expert of National Natural Science Foundation of China peer review expert of national "863" project vice chairman of Expert Committee (preventive medicine) of medical postgraduate teaching resources construction in Colleges and universities vice chairman of Jilin Preventive Medicine Association director of the Third Council of Jilin anti cancer association chairman of Health Engineering Professional Committee of Jilin Preventive Medicine Association Health Engineering Professional Committee of Jilin Preventive Medicine Association Chairman of health and toxicology professional committee, chairman of public health education professional committee of Jilin Preventive Medicine Association, standing member of Health Management Professional Committee of Jilin Preventive Medicine Association, member of Environmental Medicine Professional Committee of Jilin Environmental Science Association, vice president of Jilin health and economic society, member of water related product safety evaluation committee of Jilin Province, cosmetics evaluation committee of Jilin Province Committee member member of Jilin Province Science and technology progress award Review Committee member of Jilin Province anti cancer association member of Chinese medical science and Technology Award and Chinese medical Youth Award Review Committee member of public health education branch of Chinese Preventive Medicine Association member of medical ethics committee involving human body of Jilin Provincial Department of health member of Standing Committee of Health Management Professional Committee of Jilin Preventive Medicine Association member of Chinese Preventive Medicine Association Chief editor of medical research, deputy director of editorial board of Journal of Jilin University (Medical Edition), editorial board of Chinese Journal of experimental diagnostics, editorial board of Chinese Journal of health engineering, editorial board of Chinese Journal of higher medical education, editorial board of Chinese Journal of medical education, editorial board of Chinese Journal of biological products, editorial board of Chinese Journal of public health, editorial board of modern preventive medicine Editorial board member of canceration, distortion and mutation

Lecture course

Basic toxicology (Bilingual), molecular toxicology, emergency response system for public health emergencies, analytical chemistry, instrumental analysis and professional foreign languages (undergraduate and postgraduate teaching).

Research direction

In order to promote the application of nano materials in the field of biomedicine and reduce the harmful effects of nano materials on the healthy environment, we should carry out the research on the biological effects of Engineering nano materials and the toxicological safety evaluation of nano materials.

Main contributions

research project

1. Experimental study on cadmium chloride induced mitochondrial injury and apoptosis in hepatoma cells, key laboratory project of Jilin Provincial Department of health, 2009-2010, instructor 2. Myocardial ischemia / reperfusion injury and regulation of calcineurin signaling pathway, doctoral young teacher foundation, 2008-2011, instructor 3. Methylmercury induced brain development injury and PKC and can mediated negative regulation of cell cycle, National Natural Science Foundation project, 2008-2010, project leader 4. Endoplasmic reticulum mediated cadmium induced apoptosis of liver cancer cells and its mechanism, NSFC youth fund project, 2008-2010, instructor 5. Research and development of new rare earth heteropoly compounds against hepatitis B virus, project of Jilin Provincial Planning Commission, 2008-2010, second place 6. Engineering nanomaterials Safety evaluation and control technology Jilin Provincial Administration of work safety project, 2007-2009, project leader 7. Research on safety production management and occupational hazard prevention technology of benzene and metabolites, State Administration of work safety project, 2007-2009, project leader 8. Toxicity and safety evaluation of nano materials, international cooperation project, 2007-2009, Chinese leader 9. Overseas Short term expert project, NSFC, 2007-2009, project leader 10. Research and safety evaluation of drug delivery system based on nanotechnology, national key basic research and development program (973 Program) molecular aggregation chemistry: molecular self-assembly and assembly function, 2006-2010, sub project leader 11. Research on health hazard monitoring technology of key environmental chemical pollutants in China, National Science and technology support program, 2006-2009, third place

Academic papers

Zhang Jing, Wang Hua, Huang Wei, Guo Caixia, Zhang Jianxin. Effects of benzo (a) pyrene on hepatocyte apoptosis and lipid peroxidation. Occupational health, 2009,25 (10): 1036-1037. Wang Wen, guteroberdurster, Liu Xiaomei, sun Lei, Du Haiying, Zhang long, Yang Wensheng, sun Zhiwei. Effect of nano-SiO2 on cytotoxicity of rat alveolar type I epithelial cells. Chinese Journal of occupational diseases, 2009,28 (2): 13-16, Du Haiying, Liu Xiaomei, Jin Minghua, Liu Ying, sun Zhiwei. The effect of methylmercury on the oxidative stress of HL-7702 cells. Journal of toxicology, 2009,23 (1): 37-39. sun Lei, Wang Wen, Liu Xiaomei, Jin Minghua, Du Haiying, Peng danbing, sun Zhiwei. Study on the apoptosis of HL-7702 cells induced by methylmercury and its related mechanism. Chinese Journal of preventive medicine, 2009,43 (1): 61-64. Huang Wei, Wang Hua, Guo Caixia, Jin Minghua, sun Lei, Du Haiying, Liu Xiaomei, sun Zhiwei *. Apoptosis of H9c2 cells induced by cadmium in rats. China public health, 2009,25 (1): 96-98. Liu Xiaomei, Jin Minghua, Du Haiying, Liu Ying, Wang Wen, sun Zhiwei *. Inhibitory effect of cadmium chloride combined with cisplatin on proliferation of human hepatoma cells. Carcinogenesis, aberrance, mutation, 2008, 20 (2): 100-0102. Zhang Jianxin, Jin Minghua, Du Haiying, Liu Xiaomei, Wang Wen, sun Zhiwei *. Toxic effect of methylmercury on male mouse germ cells. Journal of Jilin University, 2008,34 (5): 767-772. Yang Huaining, Xu Hui, Pu Yun, Yu Xianghui, Zhang Yu, Zhao Dali, sun Zhiwei *. Expression and activity identification of HIV polyclonal antibody in situ homologous sequence synthesis gene. Journal of Jilin University (Medical Edition), 2008,34 (5): 767-772, 34 (2): 221-225. Guo Caixia, Li Yanbo, Du Haiying, Liu Ying, sun Lei, Jin Minghua, sun Zhiwei *. Effect of Smac gene overexpression combined with cisplatin on proliferation and apoptosis of hepatoma cells. Chinese Journal of Hepatology, 2008,16 (9): 674-677. Guo Caixia, Li Yanbo, Liu Xiaomei, Liu Ying, Du Haiying, Gong Shouliang, sun Zhiwei *. Construction and expression of full-length eukaryotic expression vector of human Smac gene, 24 (11): 1328-1330. Guo Caixia, Li Yanbo, Wang Hua, Feng Xing, Huang Wei, sun Zhiwei *. Cloning of rat Smac gene and its expression in H9c2 cells. Journal of Jilin University (Medical Edition), 2008,34 (3): 369-373. Liu Xiaomei, Liu Ying, Du Haiying, Jin Minghua, Wang Wen, Peng danbing, Yu Guangyan, sun Lei, sun Zhiwei *. Oxidative damage of cadmium chloride on human hepatoma SMMC-7721 cells. Journal of toxicology, 2008, 22 (5): 337-339. Du Haiying, Jin Minghua, Liu Ying, Liu Xiaomei, Wang Wen, sun Zhiwei *. Experimental study on anti-tumor effect of cadmium chloride in vivo. Modern preventive medicine, 2008,19 (35): 3763-3765. Yu Xihe, Wu Di, Han ZHENGBO, sun Zhiwei *. Study on anti hepatitis B virus activity and in vitro toxicity of a new polyoxometalate (pom-2). Experimental diagnostics.20

Chinese PinYin : Sun Zhi Wei