Zhang Baorong

Zhang Baorong

Zhang Baorong, male, Professor, chief physician and doctoral supervisor of the medical department of Zhejiang University, director of the Department of Neurology of the Second Affiliated Hospital of Medical College of Zhejiang University, is a member of China Alzheimer's disease association (ADC).

Personal profile

He graduated from the Department of clinical medicine of Zhejiang University in 1988 and has been engaged in clinical, scientific research and teaching work in the Department of biomedical engineering of Medical College of Zhejiang University and the Department of Neurology of the Second Affiliated Hospital since 1988; From 1999 to 2001, he was engaged in the clinical and experimental research of Parkinson's disease in the laboratory of motor control, Department of Neurology, Kiel University, Germany. He was promoted to chief physician in 2005, professor and doctoral supervisor in 2006. he has been engaged in the research and treatment of clinical neurological diseases, especially in the diagnosis and treatment of difficult and critical diseases; he has explained the motor control theory of Parkinson's disease, Published a series of high impact articles, which have important guiding significance for clinical treatment; established the main types of cerebellar ataxia in China; located the gene locus of neuronystagmus, which has important guiding significance for clinical disease localization; also has deep research on the diagnosis and treatment of vascular malformations (spinal cord and brain, etc.), multiple sclerosis, peripheral neuropathy, etc. Chinese Journal of Neurology, Chinese Journal of emergency medicine, hereditas and other special reviewers, member of Zhejiang Neurology Society, visiting professor of State Key Laboratory of medical genetics.

Mainly engaged in

(1) Early diagnosis, treatment and molecular basis research of Parkinson's disease, Alzheimer's disease, Huntington's disease and so on; (2) clinical diagnosis and treatment of critical and difficult neurological diseases such as cerebrovascular disease and peripheral neuromuscular disease. He has been working in the clinical front line for 20 years, and has been engaged in the research and treatment of clinical diseases, especially the diagnosis and treatment of difficult and critical diseases. He has made important contributions and saved the lives of many critical patients. Recently, we have strengthened and participated in the scientific research and cooperation on neuroinformation engineering in the Institute of higher studies of Zhejiang University. In the field of academic research, he has made contributions in the following aspects: with Professor deuschl of Germany, he proposed the movement control theory of Parkinson's disease, the pathogenesis of tardive dyskinesia, and the relationship between subthalamic nucleus and Madopar dose. His papers were published in brain, 2002, 125:871; annofneurol, 2002, 52:240; movdis, 2003, 18: 1162 has been cited by him for more than 100 times, which has important guiding significance for clinical treatment; it evaluates the relationship between different clinical phenotypes of Parkinson's disease and the molecular genetic nature of the disease, and explains the reasons for the different effects of drug treatment, Move.Dis Etc.). SCA3 / MJD gene mutation was detected for the first time in presymptomatic hereditary spinocerebellar ataxia. The paper was published in Chinese Journal of Neurology, etc., and proved to be the main gene type of spinocerebellar ataxia in Chinese, which has been listed in the national authoritative textbook of neurogenetics. The clinical, imaging features and gene mutation of Huntington's chorea family were systematically studied. The paper was published in Chinese Journal of Neurology; Yichuang et al. This paper systematically studied the clinical diagnosis and treatment characteristics of cerebrovascular diseases, and published in (Chinese Journal of Neurology; Zhejiang unimedsci, etc.). We also conducted a series of studies on congenital nystagmus. First, we published clinical research results in hereditary, then published gene mapping articles in humangenet, and recently published two new FRMD7 gene mutation types in molvis et al. Which were the first reports in the world. Therefore, we identified FRMD7 gene mutation in Chinese CMN patients, and further proved that FRMD7 gene mutation is cm This research achievement has been included in the international mutation database, named hm070040 and hm070041 respectively. At present, it has been cited by SCI for more than 20 times (e.g Nat.genet Recently, a new splice of FRMD7 gene was found, which has been included in UniGene database (named fj717411.1). In addition, more than 1500 databases of nervous system diseases have been collected and established in recent 10 years, which has preserved precious genetic resources and laid a foundation for further research.

Chinese PinYin : Zhang Bao Rong