Xiangjiapi

Chinese Name: cortex Periplocae

[category] skin

[synonym] cortex Acanthopanax, cortex Periplocae (scientific folk herb), cortex Acanthopanax (Shandong traditional Chinese Medicine), cortex Acanthopanax (Shanxi Traditional Chinese medicine records), cortex Acanthopanax (Sichuan Traditional Chinese medicine records).

[source] the root bark of Periploca sepium (Asclepiadaceae).

[plant morphology] Periploca paliurus, also known as narrow leaf Luo?, yangnaitiao, chouai, yangjiaohuai, yangjiaoye.

Fallen leaves twining shrubs, up to more than 1 meter high. The taproot is cylindrical. Branchlets often opposite, yellowish brown, with fine stripes, and round punctate lenticels on the branches. Leaves opposite, petiole 3-6 mm long; leaf blade lanceolate or oblong lanceolate, 5-10 cm long, 1-3 cm wide, apex acuminate, entire, base cuneate or suborbicular, dark green above, glossy, light green below, pinnate, reticulate veins more dense. Cyme axillary or terminal, one or several flowers; bracts opposite, small; pedicel thin and weak, flower diameter about 2 cm; calyx deeply 5-lobed, lobes ovate; corolla outer green yellow, inner purplish red, deep 5-lobed, lobes oblong, outer involute, margin densely white pilose; accessory corolla 5, linear, villous; stamens 5, coniform, hairy, enclosing pistil; ovary The stigma is connate. Follicles terete medially, apically 10-15 cm, joined by two follicles when relatively long. Seeds narrowly fusiform and flat, dark brown, tufted with long white hairs at the top. The flowering period is May. The fruiting period is September.

It grows on dry hillside, sandy land and gravel hillside. Distributed in Jilin, Liaoning, Inner Mongolia, Hebei, Shanxi, Henan, Shaanxi, Gansu, Ningxia, Sichuan, Shandong, Jiangsu and other places.

[collection] both in spring and autumn. When it is fresh, beat it with a wooden stick to separate the root bark from the wood, remove the wood core, and dry the skin in the shade or in the sun.

[herbal medicine] the dried skin is long cylinder, single or double roll, a few are groove or fragment, the length is up to 16 cm, the thickness is 2-5 mm. The outer surface is grayish brown or earthy brown with reddish, rough, with long transverse pores. The cork is often scaly, sometimes exposing earthy brown skin; the inner surface is grayish yellow or earthy brown. The fracture surface is slightly flat. It has strong special aroma, long smell makes people dizzy and bitter. It is better to have thick strip, thick skin, reel shape, no wood core, thick aroma and bitter taste.

It is mainly produced in Shanxi, Henan, Hebei and Shandong. In addition, it is also produced in Sichuan, Gansu, Hunan, Liaoning, Jilin, Jiangsu and other places.

This product is used as Acanthopanax senticosus skin in many places, but it is poisonous and different from Acanthopanax senticosus skin in character, so it should be used differently. See "Wujiapi".

[chemical constituents] stem bark and root bark contain more than ten glycosides. The known structures are cardiac glycoside Periplocoside and saponin Periplocoside K, H1 and E. It also contains 4-methoxysalicylaldehyde, α - geraniol, β - geraniol, α - geraniol acetate, β - geraniol acetate, β - sitosterol and glucoside.

(1) cardiotonic effect

Periploca preparation (a water-soluble substance extracted with ether and ethanol) caused the heart of the frog in situ to stop systole. The heart pressure of the cat in situ increased, the cardiac contractility increased, and the minute output of the heart (cardiopulmonary apparatus) of the cat in failure increased. The extract B (extracted with chloroform and ethanol) also has the general cardiotonic effect in the heart of eutopic cats. The effects of roxithin and roxithin from the root bark of Periploca hellenica were rapid, short lasting and weak accumulating.

② Sedative effect

Extract B of Periploca sepium has no sedative effect on mice. Both Periploca sepium tincture and Periploca sepium solution show central excitation, which may be caused by its volatile components.

③ Other functions

Roxithin can increase pulmonary circulation under certain conditions. In clinic, the same fashion of strengthening heart is beneficial to the function of excrement. In addition, Periploca sepium has insecticidal effect.

④ Biological activity

The cat unit of Periploca preparation is 0.176 G. 6 mg / kg. One gram of daucosteroside contains 5780 cat units, with low accumulation and shorter action time than that of daucosteroside G.

[toxicity] the root bark of Periploca sepium (beiwujiakang) was used to replace the bark of Acanthopanax spp. (Acanthopanax family) or the root bark of Acanthopanax spp. It is necessary to be careful when making Acanthopanax senticosus wine. Because Acanthopanax senticosus has a strong cardiotonic effect, it is easy to be poisoned if it is used too much. After injection, the blood pressure of the animals increased to a very high level, and they died in about 3-20 minutes.

[processing] clean impurities, wash with water, cut into sections after moistening, and dry in the sun.

It's hard, slightly warm and poisonous.

① Sichuan Traditional Chinese medicine annals: "it is mild in nature, sweet in taste and toxic. "

② Hebei Traditional Chinese Medicine Manual: "warm in nature, pungent in taste. "

③ "Shaanxi, Gansu, Ningxia and Qinghai herbal medicine selection": bitter and pungent in taste, warm in nature and toxic. "

Functions and indications: dispel wind and dampness, strengthen muscles and bones. Treatment of rheumatoid arthritis; children's weakness, foot flaccid line late; edema adverse urination.

① "Sichuan Traditional Chinese medicine annals": "analgesia, in addition to rheumatism. Treatment of wind cold dampness Bi, foot and knee contracture, muscle and bone pain. "

② "Selected Chinese herbal medicine of Shaanxi, Gansu, Ningxia and Qinghai": dispelling wind and dampness, strengthening muscles and bones, strengthening waist and knee. "

[usage and dosage] oral administration: decoct soup, 1.5 ~ 3 yuan; soak in wine or into pills or powder.

[taboo] "blood heat and hyperactivity of Yang should not be used. "

[prescription selection] ① for rheumatoid arthritis and joint contracture pain: Acanthopanax senticosus, Dioscorea nipponica and Dictamnus dasycarpus each cost five yuan. Soak in Baijiu for 24 hours. Take 10 ml every day.

② Treatment of weakness, foot flaccidity line late: acanthopanax bark, papaya, Achyranthes bidentata, etc. is divided into the end. One for each, three times a day.

③ Treatment of edema, urine adverse: North acanthopanax bark, tangerine peel, ginger skin, Poria cocos skin, abdominal skin each three money, water decoction. (1) selected Chinese herbal medicines of Shaanxi, Gansu, Ningxia and Qinghai

④ Treatment of edema: Xiangjiapi one money five to three money. Take it by frying. (commonly used Chinese herbal medicine in Shanghai)

Chinese PinYin : Xiang Jia Pi