Thunder pill

Thunder pill

(Ben Jing)

[synonyms] Lei ya (fan Zi Ji ran), Lei Shi (Wu Pu Ben Cao), Zhu Ling (Gang Mu), Zhu Lin Zi, Zhu Ling Zhi (records of traditional Chinese Medicine), Mu Lian Zi (records of Guangxi Traditional Chinese Medicine).

[source] it is the sclerotia of Boletus sp.

[plant morphology] leiwanella

The nucleosome is usually irregular hard block shape, askew spherical or askew ovate, 0.8-2.5 cm in diameter, rarely up to 4 cm, black brown on the surface, with fine longitudinal lines; the inner surface is closely intertwined mycelium, waxy white, translucent and slightly sticky, with the same color texture. After overwintering, a new fruiting body is produced from the nucleus of the fungus, which is not easy to see.

Most of them are parasitic on the roots of diseased bamboo. It is distributed in the provinces south of the Yangtze River Basin, Gansu, Shaanxi, Hubei, Henan and other places.

[collection] spring, autumn and winter can be harvested, but autumn is the most. The diseased bamboo with withered and yellow branches and leaves should be selected and the root sclerotia should be excavated. Wash and dry after harvest.

[medicinal materials] the dried sclerotia is spherical or irregular, with different sizes and 1-2 cm in diameter. The surface is purplish brown or grayish brown, with slightly raised network wrinkles. The material is solid and heavy, not easy to break; the cross section is not flat, powdery white or light grayish yellow, granular or powdery. Those with tight texture are translucent, with translucent and opaque parts interlaced into texture. It has no Qi and light taste. At the beginning of chewing, it has a granular feeling and is slightly mucinous. After chewing for a long time, it will melt without residue. It is better to be big, plump, hard, UV brown, white inside and without sediment.

It is mainly produced in Sichuan, Guizhou, Yunnan, Hubei, Guangxi and Shaanxi. In addition, it is also produced in Zhejiang, Hunan, Guangdong, Anhui, Fujian and other provinces.

[chemical composition] it contains 6.5% moisture, 4.0% ash, 0.6% ether extract and 22% alcohol extract.

The main component is a kind of protease, called leiwansu, which is about 3% in content. It is an effective component to drive cestode and fails to work when heated. 0.06 μ g in 10 ml weak alkaline (pH8) solution can decompose protein.

[pharmacological action] 1

When the cestode was put into the extract of 5-30% leiwan at 37 ℃, the fast one died after 2 hours and 40 minutes, and the slow one died after 9 hours. However, it could survive for 40-62 hours in normal saline and 24-30 hours in distilled water. Leiwan can expel human and canine Taenia. Most of the worm bodies discharged after taking Lei Wan will not move when they are put in the mild temperature normal saline, and the degree of damage to the details is the most significant. Therefore, the anti Taenia effect of Lei Wan is not to paralyze the worm body, but due to the decomposition of protein by the protease in Lei Wan, resulting in the destruction of scolex.

② Effect on Ascaris lumbricoides

In vitro test was effective for Ascaris suum, but not for Ascaris suum infection.

③ Anti Trichomonas vaginalis effect

After 5 minutes, most of the worms were granulated and deformed, and some of them were still active.

[processing] remove impurities, wash and moisten, slice and dry; or wash and dry, mash when used.

"Lei Gong Pao Zhi Lun" says, "every Xiaowan is soaked in licorice overnight. The black skin is scraped with a copper knife and broken into four or five pieces. He soaked it in licorice Soup for one night and steamed it until it came out. Day dry, but mixed with wine, as before from already to not steamed, day dry with. "

Bitter, cold and poisonous.

① Ben Jing: "it tastes bitter and cold. "

② Bielu: "salty, slightly cold, with little poison.

③ "Gangmu": "Gan Wei Ku, Ping. "

④ Yilin zuanyao: "bitter, sour, salty, cold. "

[channel tropism] entering stomach and large intestine.

① "Ben Cao Hui Yan": "start with, foot Yang Ming Jing. "

② "Lei Gong processed medicine solution": "into the lung, spleen, stomach three channels. "

③ Yuluo Yaojie: "start with Shaoyin heart, foot Jueyin liver meridian. "

[function indications] eliminate accumulation and kill insects. It can cure abdominal pain, malnutrition and wind epilepsy.

① Ben Jing: "it can kill three insects, expel poisonous gas, heat in the stomach, benefit husband, and disadvantageous woman. It can be used as ointment to eliminate all kinds of diseases in children. "

② Bielu: "the evil spirit is driven away, the evil wind perspires, the heat in the skin is removed, and the accumulation of white insects and inch White is not stopped. "

③ "Theory of medicinal properties": "it can chase the wind, control epilepsy, and kill Ascaris lumbricoides. "

④ Yucatalpa medicine solution: "clearing heat and soothing liver, killing cunbaichong, body wind removing epilepsy, stopping children's sweat. "

⑤ "Shaanxi traditional Chinese medicine annals": "Xiaoji Shachong, Qingre Jiedu. It is effective in treating abdominal pain, infantile malnutrition and heat in the stomach. "

[usage and dosage] oral administration: decoction, 2-3 Qian; or into pills, powder. External use: powder puff or fried water wash.

[should avoid] it should be taken with caution if there is worm accumulation and deficiency cold of spleen and stomach.

① Bielu: "taking it for a long time makes people impotent. The red man kills. "

② "Li Shi and Hou Pu are the envoys of the book of Materia Medica. Kudzu root. "

③ "On medicinal properties": Evil (sharp) storage, (GE) root. Daphne genkwa is an envoy. "

④ "Introduction to medicine": "taking medicine for a long time hurts Yin, both men and women are the same. "

⑤ "If diseases and insect pests accumulate for a long time and the spleen and stomach are exhausted, it is also forbidden to use it. "

[prescription selection] ① xiacunbaichong: the leiwan is made by soaking it in water, peeling it, cutting it and baking it at the end. In case of any disease, the first step is to eat a little fried meat at the beginning of the fifth night, and then take it with one coin of medicine and porridge. (experience ahead)

② Cure three insects: Thunder pill (gun) one or two, Xiong? One or two. The first two ingredients are daoluo powder. Take one dagger per serving, fried corn on an empty stomach, and drink it. Take one at noon and one at night. (Lei Wan San, Shengji Zonglu)

③ Xiaochanci insecticidal: Lei Wan, Shi Junzi (gun, shell), crane louse, Torreya meat, betel nut, etc. Medicine for fine powder, each take a money, warm rice drink, milk before. (Lei Wan San in Yang's family collection)

④ To treat infantile wind epilepsy, it is necessary to control and wear eyes. The extreme cases have dozens of hair every day: leiwan and mangcao are as big as chicken's yellow, and pig's fat is one catty. The first step is to fry pig fat and remove the dross. The next step is to apply the medicine. The next step is to fry pig fat and remove the dross. The next step is to remove the dross and rub the pain. If the child doesn't know the pain, he should rub his stomach and back first, but rub the rest 50 times. Don't get close to his friends and eyes. When he is one year old, he should rub his body with silk paste. And cure the adult thief. (Lei Wan Gao in Puji Fang)

⑤ Treatment of children with cold and heat, Jingti uneasy: three points of leiwan, three points of oyster, three points of Scutellaria, three points of asarum, one or two points of Cnidium. Take a bucket of water and fry it for seven liters. Remove the dross and divide it into two degrees. Watch the temperature and use it. Take a shilling bath. Do not let the water enter your ears and eyes. Take a second bath on your back. Take a bath below your waist. Take a bath to avoid the wind and puff it with powder. (Sheng Hui Fang Lei Wan Yu Tang)

⑥ Treatment of small heat without sweat: Lei Wan 42, powder half Jin. Mash and sift, and mix with flour. (ER Wu Tong Han San in Qian Jin Fang)

⑦ Treatment of pruritus, skin rash and pain: Lei Wan, ginseng, Sophora flavescens, Achyranthes bidentata (moistening, soaking, cutting, baking), baifuzi (Canning), Fangfeng (removing fork), baihuashe (moistening, soaking, peeling, bone frying), liquorice (frying, filing) each two liang, Danshen one Liang and half. Shangjiuwei daoluo powder, take two daggers each time, and adjust the wine before eating. (Shengji Zonglu) leiwan powder

⑧ For the treatment of hemorrhoids and milk sores of rats: Thunder pill, crane louse (stir fried), one or two pieces of alum ash, one or two pieces of Gleditsia needle ash and half pieces of sulfur (Research) on the ship. Five flavors, the ramming for the powder, vinegar boiled noodles paste pills, such as Wutong big, with realgar at the end of the clothes; each serving twenty pills, hollow food before musk warm wine. (Lei Wan San, Shengji Zonglu)

Clinical application: 1

Take leiwan powder, 20g each time, take it with cold boiled water and a little sugar. Three times a day for three days. On the fourth day, take 15-20g magnesium sulfate. Clinical observation of 20 cases showed that most of the worms were completely or piecewise discharged on the 2nd and 3rd day. No worms were found after treatment, and all symptoms disappeared.

② Treatment of hookworm disease

Grind the thunder pill into a very fine powder, add appropriate amount of lactose or glucose powder, and take it with boiling water. Adults should take 60 grams of each dose once or three times (the weak can take it in 2-3 days), and take another dose every few days. 11 cases were treated in clinical trial. They took medicine more than twice. After 1-3 stool tests, except 2 cases found a small amount of eggs, the rest turned negative. However, 19 cases were also observed. The results of reexamination after taking twice were not satisfactory.

③ Treatment of enterobiasis

Take thunder pill 1 money, rhubarb 3 money, two ugly 3 money, research fine powder, mix well, get up in the morning when fasting with cold boiled water 1 time delivery service. Children can be reduced by age. 188 cases were cured except 2 cases. In general, 1-2 days after taking the medicine, the worm can be excreted, and then the symptoms disappear. During the course of taking the medicine, 13 patients had transient and mild abdominal pain.

[discussion by famous experts] 1. In the classic of materia medica: "leiwan is mainly used to kill three insects. White insects and cunbai come out of their own, and their intestines and stomach are very damp and hot. Expelling toxic gas, heat evil in the stomach, evil wind, sweating, accumulation of heat in the skin, excessive heat in the intestines and stomach, bitter cold can eliminate dampness and heat evil in the two meridians (Hand Foot Yangming), then all kinds of syndromes can be eliminated by themselves. For the treatment of all kinds of diseases in children, children like to eat sweet and fat, intestines and stomach are more damp and hot, bitter can kill insects and dehumidification, salty and cold can clear away heat and eliminate accumulation, so it is also the master. "Bielu" also said, long service makes Yin flaccid, just see its too bitter and cold, partial to the gas, can make Yang flaccid. "Besides killing insects, it is very rare. "

② "Bencaoshu" says: "the thunder pill is formed by the residual Qi of bamboo. It can clear the smell of yin and dredge the heat of Qi and blood. Isn't it a good medicine. Second, GM is not without its vitality. If you know this meaning, you can make good use of it. "

③ "Ben Jing Feng Yuan": "Lei Wan" and "Qian Jin" can't be used to treat children's typhoid fever. They should be used constantly in the treatment of prescriptions, and their function of expelling toxic gas should also be taken. "

Chinese PinYin : Lei Wan