Yang Menghua
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Yang Menghua, female, born in March 1978. Macao, China, native of Jiangmen, Guangdong. Doctor, Professor of animal science and Technology College, Zhejiang agriculture and Forestry University.
Educational experience
2005 / 9-2008 / 7: doctor, Nanjing Agricultural University, Academy of life sciences, 2002 / 9-2005 / 7: Master, China Agricultural University, Academy of life sciences, 1997 / 9-2001 / 7: Bachelor, China Agricultural University, Academy of life sciences
work experience
From February 2013 to now, Professor of School of animal science and technology of Zhejiang agriculture and Forestry University from August 2009 to January 2013, postdoctoral researcher of University of Pennsylvania, School of medicine from July 2008 to August 2009, assistant researcher of Lehman College, City University of America
Research direction
1. Expression regulation mechanism of Vibrio cholerae toxin gene 2. Interaction between intestinal pathogens and conditional pathogens 3. Discovery of unknown proteins in quorum sensing
Lead the project
1. Research on the regulation mechanism of Vibrio cholerae aphB protein on oxygen chemotaxis, talent start project, 2013-2016, with a fund of 500000 yuan. 2. Research on the regulation mechanism of Vibrio cholerae aphB protein on oxygen chemotaxis, NSFC general program, Youth Science Foundation, 2014-2016, funding 230000 yuan . 3. Research on molecular regulation mechanism of bile acid mediated gene expression of Vibrio cholerae toxin, NSFC, 2015-2018, funding 850000 yuan
Published articles
1.YangM.H.,LiuZ.,HughesC.,SternA.,WangH.,ZhongZ.T.,KanB.,FenicalW.,ZhuJ.2013.Bilesalt-inducedintermoleculardisulfidebondformationactivatesVib riocholeraevirulence.Proc.NatlAcad . Sci.USA .(IF9.8)110(6):2348-2353 2.LiuZ.*,YangM.H.*,PeterfreundG.L.,SelamogluN.,DaldalF.,ZhongZ.T.,KanB., ZhuJ.2011.Vibriocholeraeanaerobicinductionofvirulencegeneexpressioniscontrolledbythiol-basedswitchesofvi rulenceregulatorAphB.Proc.NatlAcad . Sci.USA (if9.8) 108 (2): 810-815 * co first author: Yang M.H., Frey E.M., Liu Z., bishar R, andZhuJ.2010.ThevirulencetranscriptionalactivatorAphAenhancesbiofilmformationofVibriocholeraebyactivatingtheexpressionofthe biofilmregulatorVpsT.InfectionandImmunity .(IF4.1)78(2):697-703 4.YangM.H.,GielJ.L.,CaiT.,ZhongZ.T., ZhuJ.2009.TheLuxR-familyquorumsensingactivatorMrtRrequiresitscognateautoinducerfordimerizationandactivationbut notforproteinfolding.JBacteriol .(IF3.7)191(1):434-438 5.YangM.H.,SunK.J.,ZhouL.,YangR.F.,ZhongZ.T., ZhuJ.2009FunctionalanalysisofthreeAHLautoinducersynthasegenesinMesorhizobiumlotirevealstheimportantroleofquorumsensingi nsymbioticnodulation.CanadianJournalofMicrobiology (IF1.2)55(2):210-214 6.CaoH.J.*,YangM.H.*,ZhengH*.M.,ZhangJ.,ZhongZ.T., ZhuJ.2009.ComplexquorumsensingregulatorysystemsregulatebacterialgrowthandsymbioticnodulationinMesor hizobiumtianshanense.ArchivesofMicrobiology (if1.8) 191 (3): 283-289 * co first author: 7. Luh. Y., Luo L., Yang M. H., Cheng H. P. 2012sinorhizobium meliloti exoristhe target of PE riplasmicproteolysis.JBacteriol .194(15):4029-4040 8.YangM.H.,ZhongZ.T., ZhuJ.2006.RecombinantexpressionofanautoinducersynthaseofMesorhizobiumlotiinEscherichiacoliandanalysisoftheautoinducerproduce dinrecombinantstrain.JournalofMicrobiology (Chinese)46(6):1007-1010 9.YangM.H.,LiY., GuanG.H.2005.High-levelExpressionofanextreme-thermostablexylanaseBfromThermotogamaritimaMSB8inEscherichiac oliandPichiapastoris.JournalofMicrobiology (Chinese)45(2):236-240
Chinese PinYin : Yang Meng Hua
Yang Menghua