Wang Jun
Wang Jun
Wang Jun, researcher, doctoral supervisor, national fund for Distinguished Young Scholars winner, 973 chief scientist; former CEO of BGI, President of BGI Research Institute; visiting professor of Copenhagen University and University of Hong Kong.
On October 27, 2015, its entrepreneurial company "carbon cloud Intelligent Technology Co., Ltd." was officially established in Shenzhen.
On October 10, 2019, it was announced that Wang Jun ranked 444 with a wealth of 9 billion yuan.
On February 26, 2020, with a wealth of 10 billion yuan, it ranked No. 2000 in the 2020 Shimao Shenzhen Hong Kong International Center · Hurun global rich list.
Personage introduction
Its research involves genomics, bioinformatics, big data analysis, machine learning and artificial intelligence. The scientific issues involved include "what is a gene? How do genes evolve at the level of species, individual and cell under various evolutionary pressures? " The relationship between human genes and complex phenotypes? Including complex diseases, cancer, agricultural animal and plant traits, and the relationship between human symbiotic microorganisms and health "Bioinformatics analysis methods and databases: genome data analysis, tools and database development, including assembly, annotation, comparison, polymorphism, expression, epigenetics, regulation and evolution."
The story of the characters
Wang Jun entered Peking University for undergraduate study in 1992 and graduated in 1997. He was recommended to study for a master's degree in artificial life at Peking University, and then continued to study for a doctor's degree at Peking University. As an undergraduate, he majored in computer and artificial intelligence. In the spring of 1999, when our country began to undertake 1% of human gene determination, there was an urgent need for compound talents with both biological background and computer proficiency. During his master's degree, Wang Jun was naturally sent to participate in the research of this work. Since then, he began to form an indissoluble bond with bioinformatics, and undertook part of the data analysis work in China in the human genome project. Then in 2001, he was responsible for the bioinformatics analysis part of China indica rice genome project. At the beginning of 2003, Professor Wang Jun, as one of the main participants in the early diagnosis of SARS, completed the genome decoding of four coronaviruses closely related to SARS in a short time. At the same time, scientific research on early diagnosis of SARS was carried out, and 300000 copies of "immunoassay kits" were sent to the first line of prevention and treatment of SARS free of charge at the fastest speed. In the struggle against SARS, he took up the important weapon of science and technology, stuck to the front line and made contributions to the prevention and control of SARS. Professor Wang Jun also organized and implemented the silkworm and pig genome project and chicken polymorphism mapping project, developed a number of software algorithms including assembly, comparison and annotation, and established a number of databases. The above scientific research achievements were published in "nature", "science", "nature review genetics", "PLoS Biology", "plantcell", "genome research", "Nuclear acids research" and other top magazines in the world.
From June 2007 to November 2008, Professor Wang Jun led the team to complete the first yellow human genome research project - "Yanhuang 1" in Shenzhen.
From 2009 to 2012, Professor Wang Jun led the scientific research team to successively complete a series of projects such as the international giant panda genome project, cucumber genome project and silkworm genome re sequencing project. At the same time, he put forward the concept of human "Pan genome", sequenced the ancient Eskimo genome in Greenland about 4000 years ago, and carried out the "human intestinal metagenome" in cooperation with the European Union These achievements are also published in nature and science.
After 2012, the major projects being organized and implemented are: "million omics project", "metabonomics level research project of metabolic diseases and other quantitative traits", "single gene and individual level cancer research project", "genomic polymorphism research of East Asian population", thousand species of animals and Plants Genome Project, thousand species of single gene disease genome project, "intestinal microbiological research project" "As well as a number of polymorphic maps and molecular breeding programs (including rice, silkworm and pig genomes), etc.
In 2013, he led the team to successfully acquire the US listed company: completegenomics.
On July 17, 2015, Wang Jun resigned as president of BGI Research Institute and CEO of BGI. The board of directors of BGI decided to support the establishment of a new business organization with artificial intelligence as the core and focusing on forward-looking business development led by Wang Jun.
On October 27, 2015, the start-up company "carbon cloud Intelligent Technology Co., Ltd." was officially established in Shenzhen.
Scientific achievements
Wang Jun has been engaged in the research of genomics and bioinformatics since he was a graduate student in 1999. He has published more than 300 papers in professional journals, including more than 100 first author or corresponding author. Among them, more than 100 articles (20 cover articles) were published in science, nature, cell and NEJM.
Related reports
Wang Jun
He was born in June 1976 in Dongtai City, Jiangsu Province. In 2002, he received a doctor of Science degree from school of life sciences, Peking University. In 2004, he was promoted to research fellow, President of Shenzhen Huada Institute of genomics, and 973 chief scientist. He is mainly engaged in the scientific research of bioinformatics algorithms and tools, comparative genomics, molecular evolution, the relationship between genes and complex phenotypes, and the relationship between human symbiotic microorganisms and health.
Since taking part in the international human genome project, we have jointly launched a number of major scientific research projects such as "international thousand human genome" and EU metahit. In the study of human intestinal flora, it is the first time to systematically explain the "reference gene set" of "human second genome" - intestinal flora and the polymorphism of intestinal flora in the population, to carry out the "metagenome association analysis" of intestinal flora and type II diabetes, and to put forward the concept of "metagenome linkage group", which opens up a new model for exploring the pathogenic factors of complex diseases.
He has published more than 260 academic papers in SCI journals, cited more than 30000 times, and applied for and authorized more than 100 patents at home and abroad. Among the major scientific research achievements, ten were selected as "top ten scientific and technological progress in the world" and "top ten scientific and technological progress in China", six were selected as "top ten international scientific and technological news" and "top ten domestic scientific and technological news", and three were selected as "top ten basic scientific research news in China". He won the China Youth Science and technology award, Tan Jiazhen Life Science Innovation Award, Zhou Guangzhao Foundation Science and technology award, Hong Kong Qiushi science and Technology Fund "Qiushi outstanding science and Technology Achievement Award" and World Chinese influence award.
Reference gene set of intestinal flora genome and its relationship with type II diabetes mellitus
abstract
The pathogenic factors of complex diseases include genetics, environment, diet and their interactions. Wang Jun and his team have carried out a lot of research work on the genetic factors of diseases from multiple omics levels by using the second generation sequencing technology, and achieved a series of results. The role of environment, diet and other factors in diseases has always been a world problem. Wang Jun and his team started with the human intestinal microbiota, which is closely related to human body. Through a series of work such as building research platform, developing bioinformatics algorithm, data processing and functional analysis, they constructed the world's first "reference gene set" of human intestinal microbiota, including more than 3 million genes and the polymorphism and similarity of different individual intestinal microbiota, and preliminarily explained the intestinal microbiota And human health. In order to further explain the relationship between complex diseases and intestinal flora, Wang Jun and his team took type II diabetes as the research object, initiated the method of "metagenomic association analysis" (mgwas) to compare diabetic patients with normal people, and first proposed and applied the concept of "metagenomic linkage group (MLG)" to clarify the relationship between type II diabetes and intestinal flora, and the relationship between patients and healthy people The differences of intestinal microbial composition in ordinary people, the biomarkers found provide a new method for the clinical treatment of type II diabetes in the future, and some of the findings are being further functional research, laying the foundation for the prevention and treatment of diabetes in the future. This study provides a new strategy for the functional prevention and treatment of other complex diseases at the level of intestinal flora. This achievement was awarded the "most influential research award" of the top ten diabetes researches in China in 2012.
personal honor
2012 top 10 most influential research awards of diabetes in China
Tan Kah Kee Science Award 2013, 2014
Tan Jiazhen Life Science Innovation Award 2013
Mayor's award of Shenzhen Science and technology award 2013
Fortune 2013: 40 elites under 40 in 2013
2013 scientific Chinese: "scientific Chinese 2012 person of the year"
2013 Thomson Reuters: one of the hottest scientific figures
2012 top 10 most influential research awards of diabetes in China
2013 China Association for science and technology: Zhou Guangzhao science and Technology Award
2013 "influence the world Chinese Award" in the field of scientific research
2012 nature: Top 10 scientists of the year in 2012
Guangdong in 2012 and 2012
Chinese PinYin : Wang Jun4
Wang Jun
