Kong Lingdong

Kong Lingdong

Kong Lingdong, female, doctor, professor and doctoral supervisor of School of life sciences, Nanjing University. He is mainly engaged in the research of antidepressant and gout of traditional Chinese medicine. He is also committed to the research of processing, preparation and fingerprint of traditional Chinese medicine.

Character experience

In 1985, 1990 and 1996, he obtained bachelor's degree, master's degree and doctor's degree in traditional Chinese medicine from Nanjing University of traditional Chinese medicine. From 1985 to 1993, he worked as a teaching assistant and lecturer in the University. In 1996, he joined the postdoctoral research center of biology of Nanjing University and was appointed as associate professor of Botany of Nanjing University in April 1998. In 2000, it was awarded the first batch of backbone teachers funding scheme by the Ministry of education. He was appointed professor in October 2003 and doctoral supervisor in April 2004.

Research direction

In the aspect of anti gout traditional Chinese medicine research, in view of the complex etiology and pathogenesis of gout, our research team took the lead in establishing the gout animal model of hyperuricemia caused by oxyzinic acid in China, and other anti gout research technology platforms, to study the anti gout effect of Huangbai and Ermiaowan, the representative prescriptions of clearing heat and drying dampness, and to provide scientific basis for clinical medication and treatment of clearing heat and drying dampness. Other anti gout components and components were found.

Main contributions

Scientific and technological achievements

From 1985 to 1996, he worked in Nanjing College of traditional Chinese medicine, and participated in one project entrusted by pharmacopoeia committee of Ministry of health, two national "Eighth Five Year" scientific and technological research projects, and three Jiangsu provincial projects. Three scientific and technological achievements appraisal projects in Jiangsu Province were completed. in 1996, when working in Nanjing University, he successively undertook and participated in more than 10 scientific research projects. In the aspect of antidepressant and gout of traditional Chinese medicine, he was responsible for completing a project of China Postdoctoral Science Foundation in 1998. In 2000, as the second host, he completed one key project of modernization and industrialization of traditional Chinese medicine of the Ministry of science and technology of the people's Republic of China and one project of provincial natural fund. From 2002 to 2003, he was responsible for completing one of the first batch of funding programs for key teachers in Colleges and universities of the Ministry of education and one national and Jiangsu Provincial Natural Science Foundation project. The results of 1999 and 2003 were excellent. As the first, the first, the second and the sixth person to complete 4 scientific and technological achievements appraisal projects in Jiangsu Province. We have applied for 5 patents on new uses of drugs in China. At present, it undertakes two projects of National Natural Science Foundation of China and one project of Jiangsu Natural Science Foundation of China. Kong Lingdong, professor and doctoral supervisor of School of life sciences, Nanjing University. Member of Phytochemistry and Resources Committee of Chinese botanical society. successively presided over three projects of National Natural Science Foundation of China, one project of the first batch of backbone teachers funding program of Ministry of education, one project of China Postdoctoral Science Foundation and two projects of Jiangsu Natural Science Foundation. As one of the hosts, he presided over one key project of modernization and industrialization of traditional Chinese medicine of the Ministry of science and technology. In addition, we have mainly participated in the completion of two key scientific and technological projects in the eighth five year plan and four other provincial and ministerial level projects. As the first, the first, the second, the third and the sixth person, they completed five scientific and technological achievements appraisal in Jiangsu Province respectively. As the first inventor, he has been granted one patent.

publish one’s thesis

(recent representative works, * corresponding author) 1. Qing Yu Zhang, Ying pan, Rong Wang, Lin Lin Kang, Qiao Chu Xue, Xiao Ning Wang, Ling Dong Kong *. Quercetininhibitsampk / txnipacitivation and reduction inflammatorylation to improve insuligning defects in the hypothalamus of high fruits- fedrats.JournalofNutritionalBiochemistry2014 ;25(4):420-428. 2.YingPan,YiHong,Qing-YuZhang, Ling-DongKong*.Impairedhypothalamicinsulinsignalingi nCUMSrats:RestoredbyicariinandfluoxetinethroughinhibitingCRFsystem.Psychoneuroendocrinology2013;38 (1):122-134. 3.WangW,WangC,DingXQ,PanY,GuTT,WangMX,LiuYL,WangFM,WangSJ, KongLD*.Quercetinandallopurinolreduceliverthioredoxin-interactingproteintoalleviateinflammationandlipidaccumu lationindiabeticrats.BritishJournalofPharmacology2013 ;169(6):1352-1371. 4.WangX,ZhangDM,GuTT,DingXQ,FanCY,ZhuQ,ShiYW,HongY, KongLD*.Morinreduceshepaticinflammation-associatedlipidaccumulationinhighfructose-fedratsviainhibitingsphingosinekinase1/sphingosine1-phosp hatesignalingpathway.BiochemicalPharmacology201315 ;86(12):1791-1804. 5.Yun-WeiShi,Cai-PingWang,LeiLiu,XingWang,YeHong,ZhenLi, Ling-DongKong*.Antihyperuricemicandnephroprotectiveeffectsofresveratrolanditsanalogue sinhyperuricemicmice.MolecularNutrition&FoodResearch .2012;56(9):1433-1444. 6.Dong-MeiZhang,Yu-ChengLi,DeXu,Xiao-QinDing, Ling-DongKong*.Protectionofcurcuminagainstfructose-inducedhyperuricaemiaandrenalendothelialdysfunctioninvolvesNO-mediatedJAK- STATsignalinginrats.FoodChemistry2012 ;134(4):2184–2193. 7.ChuangWang,YingPan,Qing-YuZhang,Fu-MengWang, Ling-DongKong*.QuercetinandallopurinolamelioratekidneyinjuryinSTZ-treatedratswithregulationofrenalNLRP3inflammasomeactivationandlipidaccumulationPLoSOne.2012;7(6):e38285. 8.Yu-JieLou,Jian-MeiLi,YanLu,XingWang,Rui-QingJiao,Shui-JuanWang, Ling-DongKong*.Aristolochicacid-induceddestructionoforganiciontransportersandfattyacidmetabolicdisor derinthekidneyofrats.ToxicologyLetters2011 ;201(1):72-79. 9.XingWang,Cai-PingWang,Qing-HuaHu,Yao-ZhongLv,Ling-DongKong*.ThedualactionsofSanmiaowanasahypouric emicagent:down-regulationofhepaticXODandrenalmURAT1inhyperuricemicmic

Chinese PinYin : Kong Ling Dong